Int Poster J Dent Oral Med 2008, Vol 10 No 01, Poster 393
Influence of Restorative Materials on Caries Development of Irradiated Teeth
Tim Fiedler, German Bundeswehr, Kiel, Germany
Prof. Dr. Hans-Günter Schaller, Department of Operative Dentistry and Periodontology, Martin-Luther-University Halle-Wittenberg
Dr. Christine Berthold, Department of Operative Dentistry and Periodontology, University of Erlangen
Dr. Christian R. Gernhardt, Department of Operative Dentistry and Periodontology, Martin-Luther-University Halle-Wittenberg
21 - 24 March 2007
IADR/AADR/CADR 85th General Session and Exhibition
"Radiation caries" is a well-known consequence of radiotherapy of
malignant tumors in the head and neck region. During the past decade, it was
recognized on patients with hip and knee prosthesis, that the radiation
effect in vicinity of implants was increased. Tissues in contact with metal
implants showed distinctive higher radiation induced defects than tissues of
patients without an endoprosthesis. Based on this findings, further
investigations will have to show, if different dental filling materials have
similar effects on human enamel and dentin.
The aim of this study was to evaluate the influence of different
restoration materials on demineralization of irradiated enamel and dentin
compared to non-irradiated teeth.
Material and Methods
Thirty-two freshly extracted human third molars without caries were used.
The teeth were assigned to four groups (n=8). Over the whole experimental
period specimen were stored in 0.9% saline. All teeth were prepared with
class II-cavities (mesial dentin, distal enamel) (Fig. 1). The specimens
were randomly assigned to four experimental groups (Fig. 2). After
preparation cavities were filled with four different materials (composite
resin, amalgam, glass ceramic inlays and gold inlays). All teeth were
bisected along their long axis in the middle of the fillings. One half of
each tooth was irradiated with 60 Gy (2 Gy/ day for six weeks), the other
half remained non-irradiated. All specimens were demineralized for 6 days
with acidified gel (HEC, pH 4.8, 37 degrees C). From each tooth, two
dentinal slabs were cut. The depth of the demineralized areas was determined
using a polarized light microscope (Fig. 3).
|Fig. 1: Specimen preparation. Standardized cavities were prepared.
|Fig. 2: All specimen were assigned to four experimental groups using different filling materials.
|Fig. 3: The experimental design including radiation, demineralization and evaluation.
In all specimens lesion depth could be recorded (Fig. 5, 6). Significant
higher lesion depths after irradation were found for the dentin and enamel
in group using amalgam as filling material(*p<0.05, **p<0.001). in the
following boxplot the evaluated lesion depths are summarized (fig. 4).
|Fig. 4: Boxplot. Lesion depths of all groups (*= significant differences to the non-irradiated control).
|Fig. 5: Image of an enamel lesion. Composite was used as filling material.
|Fig. 6: Image of an irradiated specimen restored with amalgam. The lesion is clearly visible.
||Fig. 7: Enlarged view of selected region from Fig. 6
Within the limits of an in vitro study, irradiated dentin with
amalgam-fillings showed significantly increased lesion depths after
demineralization by an acidified gel system compared to all other groups. In
all other material groups irradiation had no significant impact on
artificial dentin and enamel demineralization.
This Poster was submitted by Dr. Christian R. Gernhardt.
Dr. Christian R. Gernhardt
Department of Operative Dentistry and Periodontology
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