We are using cookies to implement functions like login, shopping cart or language selection for this website. Furthermore we use Google Analytics to create anonymized statistical reports of the usage which creates Cookies too. You will find more information in our privacy policy.
OK, I agree I do not want Google Analytics-Cookies
International Poster Journal of Dentistry and Oral Medicine



Forgotten password?


Int Poster J Dent Oral Med 20 (2018), OMD/PDA     15. Jan. 2019
Best oral communication of clinical cases Int Poster J Dent Oral Med 20 (2018), OMD/PDA  (15.01.2019)

Supplement, Poster 2019, Language: English

Regenerative Endodontic Treatment with the Use of L-PRF®
Melo-Ferraz, Antonio / Silva, Joana Borges / Santos, Carolina Borges / Jacques, Inês / Miller, Paulo Cruz
Traditionally, immature permanent teeth with necrotic pulp and apical periodontitis are treated with apexification procedures using calcium hydroxide (CaOH2) or by performing an apical barrier with Mineral Trioxide Aggregate (MTA) prior to filling the root canal . The CaOH2 apexification procedure generally encompasses multiple visits and a long period of treatment time. Prolonged treatment with CaOH2 can break the bonds between collagen fibers and dentin hydroxyapatite crystals, which leads to microhardness reduction and increased fracture susceptibility. An apical barrier with MTA shortens treatment time. The treatment of apexification with CaOH2 or apical barrier of MTA is biocompatible and bioactive, however, a procedure of apexification in immature permanent teeth with necrotic pulp, has no potential to restore the vitality of the damaged tissue in the canal space and promote root maturation (thickening of root canal walls and / or apical closure).
The European Endodontic Society (ESE) and the American Association of Endodontists (AAE) have issued position statements and clinical considerations for regenerative endodontics .
Regenerative endodontic treatment (RET) includes procedures that allow root development, increased wall thickness and apical closure. The production of totally autologous matrices using a second generation platelet concentrate known as platelet and leukocyte rich fibrin (L-PRF® - Intra-Lock International - Boca Raton, FL, USA) containing growth factors and entrapped cytokines in a free polymerization fibrin network / matrix, may increase the regeneration potential of soft and hard tissues.
We present a clinical case where modified regenerative endodontic procedures were used, using L-PRF® as a matrix and source of growth factors for treatment of a necrotic immature superior lateral incisor with open apex and associated chronic apical abscess, introducing the theme of "Bio- Obturation".

Keywords: Regenerative endodontics, immature permanent teeth, necrotic pulp and apical periodontitis, L-PRF

Poster Award: Best oral communication of clinical cases

27th Annual Meeting of the Portuguese Dental Association 2018 (OMD)
08.-10. November 2018
Exponor, Porto, Portugal