Int Poster J Dent Oral Med 20 (2018), No. 4 15. Dec. 2018
Int Poster J Dent Oral Med 20 (2018), No. 4 (15.12.2018)
Poster 1236, Language: English
Efficacy of 4% Tulsi Dentifrice on Salivary Streptococcus Mutans Count Among 14 - 15 Years School Children in Davangere City, India - a Triple Blind Placebo Controlled Concurrent Trial
NG, Bhuvaneshwari / GV, Usha / L, Nagesh
Objectives: To assess and compare the antibacterial efficacy of 4% Tulsi, commercially available fluoridated (Colgate total care) and placebo dentifrices on salivary Streptococcus mutans counts among 14-15-year-old school children in Davangere city.
Materials and methods: A triple blinded randomised controlled trial with a study population of 14-15-year-old school children. A sample of 84 participants was randomly selected and 2 ml of unstimulated saliva was collected. Microorganisms were cultured using Mitis Salivarius selective media. The participants with a 105 colony-forming units (CFU) were considered as eligible. Block randomisation and concealed randomisation methods were adopted to allocate the participants into three groups containing 28 each. After seven days, a post assessment of salivary Streptococcus mutans count was done. Wilcoxon signed rank test for within group comparison and Kruskal Wallis ANOVA for intergroup comparison were used.
Results: The study showed a significant reduction in salivary Streptococcus mutans counts from baseline to post-test (mean rank 37.95 - 25.27) in the Tulsi dentifrice group. The intergroup comparison showed a statistically significant difference (p=0.044). Post hoc analysis showed a statistically significant difference between the Tulsi and placebo dentifrice groups (p=0.026).
Conclusion: 4% Tulsi extract incorporated in the form of dentifrice have shown a maximum reduction in the salivary Streptococcus mutans count, for a period of seven days when compared to fluoridated dentifrice.
Keywords: Dentifrice, Tulsi, streptococcus mutans, dental caries, randomization
Poster Award: Late Sri Ram Ashre Singh Award
22nd National conference
03.-05. November 2017
Dhule, Maharashtra, India