Poster 550,  Sprache: Englisch
Interleukin-4RA 1902 A/G polymorphism in relation to aggressive and chronic periodontitis
Reichert, Stefan / Stein, Jamal M. / Klapproth, Jana / Zimmermann, Uta / Reichert, Yvonne / Glaeser, Christiane / Schaller, Hans-Günter / Schulz, Susanne

The interleukin-4 receptor (IL-4R) can bind both, IL-4 and IL-13. Then T-cells were stimulated to differentiate to Th2-cells which promote B-cell proliferation and antibody production. The 1902 A/G polymorphism of the gene encoded for the α chain of the interleukin-4 receptor (IL-4RA) was found associated with enhanced IL-4 receptor activity. Therefore, the aim of this study was to evaluate putative associations of this polymorphism to generalized aggressive or chronic periodontitis and five periodontopathogens. Methods: 120 patients with severe generalized periodontitis (attachment loss >6mm in >35% of the teeth, chronic periodontitis: n=53, mean age=48.9±9.8 years; aggressive periodontitis: n=67, mean age=41±9.9 years) in comparison to periodontitis free controls (n=81, mean age=46.9±10.7 years). Interleukin-4RA polymorphism was analyzed by PCR-SSP (CTS-Kit, Heidelberg). Distributions of single alleles and genotypes were calculated by Chi²-Test with Yates correction or Fisher's exact test. Subgingival bacteria were analyzed molecular biologically using micro-Ident® test (HainLifescience, Nehren). Adjusted odds ratios were determined by logistic regression with respect to established cofactors for periodontitis such as age, gender, smoking status, and plaque index. Results: The mutant allele IL-4RA 1902 G (28.3% vs. 17%, p=0.041) and the mutant genotypes GA+GG (50.9% vs. 29.6%, p=0.021) occurred more frequently in patients with chronic periodontitis. The latter association could be confirmed by logistic regression analysis (OR=2.1, 95%CI 1.2-4.0, p=0.016). In the total study cohort the genotypes GA+GG were positive associated to the presence of T. forsythia (88.9% vs. 76.75%, p=0.045). This result remained significant after logistic regression (OR=1.5 95%CI 1.2-1.9, p= 0.001). Conclusions: The IL-4RA 1902 AG polymorphism is a putative risk indicator for generalized chronic periodontitis and the subgingival occurrence of T. fosythia.

Schlagwörter: IL-4 receptor alpha, polymorphism, chronic periodontitis, aggressive periodontitis

Konferenz/Veranstaltung:
17.-18. September 2010
DGP-APRA-Herbsttagung und Symposium der klinischen Forschergruppe 208
Bonn

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 495,  Sprache: Englisch
Comparison of two different commercially available test kits to detect periodontal pathogens
Cosgarea, Raluca/Bäumer, Amelie/Zimmermann, Nils/Kim, Ti-Sun

Background: Microbiological identification of Aggregatibacter actinomycetemcomitans and other periodontal pathogens may depend on the test protocol, especially if the concentration is near the lower detection threshold. The goal of the current study was to compare the results of the microbiological testing with different test-kits in patients with severe chronic (CP) and aggressive periodontitis (AgP).
Methods: 69 Patients were recruited in the Section of Periodontology, University Hospital of Heidelberg. Inclusion criterium to participate in the study were the clinical diagnoses CP or AgP. Pocket probing depths, vertical attachment level, gingival bleeding index, plaque control record and bleeding on probing were assessed by a periodontologist. Microbiological analysis of pooled samples from subgingival plaque was performed with two different gene probe-tests according to the manufacturer's test protocol (IAI PadoTest 4.5®, Institut für Angewandte Immunologie, Zuchwill, Switzerland (PADO), and the Meridol® Periodiagnostics, GABA, Lörrach, Germany (MERI).
Results: CP was diagnosed in 49 patients, AgP in 20 patients. The periodontal pathogens Aggregregatibacter actinomycetemcomitans (A.a.), Tannerella forsythia, Porphyromonas gingialis and Treponema denticola) were identified with both PADO and MERI: Fusobacterium nucleatum and Prevotella intermedia were only assessed by MERI. With the loboratory real-time PCR-test A.a. was identified. in series 1 more patients ware tested positive on A.a. with MERI (25%) than with PADO (20.6%). In series 2 the real-time PCR (23.2%) showed a lower prevalence for A.a. than PADO (36.4%). Only 10.3% of the patients in series 1 and 17.2% of the patients in series 2 were tested positive on A.a. with both tests. The used tests showed an agreement of k=0.72 for series 1 and k=0.41 for series 2. The test-differences for the rest bacteria-species were smaller or barely present.
Conclusions: The use of a high sensitive microbiological test is important for the choice of an optimal adjunctive antibiotic treatment. In the underlying study both commercial and laboratory microbiological tests showed an incongruence regarding the identification of A.a. Differences between the tests were also proven for the qualitative microbiological detection.

Schlagwörter: periodontitis, microbiological testing, periodontal pathogens, aggregatibacter actinomycetemcomitans

Konferenz/Veranstaltung:
June 4-6, 2009
6th Congress of the European Federation of Periodontology
Stockholm, Sweden

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 454,  Sprache: Deutsch
Immunhistochemische Untersuchungen immunkompetenter Zellen im chronisch osteomyelitischen Kieferknochen
Nolting, Tim/Wermker, Kai/Joos, Ulrich/Kleinheinz, Johannes

Due to the increasing incidence the diagnosis and therapy of osteomyelitis, especially in the subacute and chronic form is an great challenge for todays medicine. So far there is no scheme for the classification of the different osteomyelitis forms and the resulting possible therapies. The aim of this study was the quantitative analysis of T-cells and their subpopulations als well as macrophages as part of the cell-mediated immunity in osteomylitic bone tissue from biopsies taking from 15 patient suffering from different forms of osteomylitis using monoclonal antibodies for CD3, CD45RO, CD8 and CD68.
The results showed that the percent of positiv marked cell compaired to the total ammount of immunocompetent cells varied with CD45R0 22%, CD3 mit 13%, CD68 5,2% and CD8 3,0%. Overall the biopsies proved a significant higher expression of secondary antibodies than the controll group.
The literature gives no clear evidence for a precise immunological reaction scheme of the human body suffering from osteomyelitis. Looking at our results we suggest a irregular and increased immun reaction leading to a permanent dysregulation of activator-inhibtor-schemes caused by autoimmunological processes. This might keep up a persistent osteomyelitic reaction of the bone. Further studies should therefore concentrate on the quantification of T-Helper-cells.

Schlagwörter: Osteomyelitis, Immunhistologie, Differenzierung

Konferenz/Veranstaltung:
1.-3.5.2008
58. Jahrestagung Arbeizsgemeinschaft Kieferchirurgie
Wiesbaden

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 449,  Sprache: Englisch
Structure design examinations of 3-dimensional textile scaffolds using for tissue engineering in vitro
Bäumchen, Frank/Gräber, Hans-Georg/Koch, Daniel

The apical growth of epithelium is a common complication following surgical parodontal therapy. Absorbable and non-absorbable membranes have been used over the last three decades as mechanical barriers to this undesired epithelial growth. Textile scaffolds seem all the more applicable, in that they allow for the local regeneration of lost tissue when colonized with autologous cells.
The aim of this study was to examine the proliferation behaviour of human gingival fibroblasts on poly glycolide (PGA) fleece samples of various thickness and porosity. The fleece samples were produced in cooperation with the Institute for Textile Technology (ITA) RWTH Aachen.

Schlagwörter: tissue engineering, polyglycolide acid, human gingival fibroblasts, cell culture

Konferenz/Veranstaltung:
22.- 24. November 2007
Jahrestagung der deutschen Gesellschaft für Biomaterialien e.V. DGBM
Hannover

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 430,  Sprache: Englisch
Molecular detection of periodontopathic bacteria in synovial fluid
Schulz, Susanne/Keyßer, Gernot/Schäfer, Christoph/John, Vera/Haffner, Maximilian/Krause, Katja/Schaller, Hans-Günter/Gläser, Christiane/Reichert, Stefan

Rheumatic diseases and periodontitis are sharing similar pathophysiological features. It is assumed that periodontopathogens could influence the aetiology of rheumatic diseases. However, the underlying pathomechanisms are still unknown. Therefore, we established a specific and sensitive method based on molecular techniques to detect 5 major periodontopathogens, Actinobacillus actinomycetemcomitans (A.a.), Porphyromonas gingivalis (P.g.), Prevotella intermedia, Treponema denticola, Tannerella forsythensis in synovial fluid.
Methods: Nine patients suffering from juvenile idiopathic arthritis or rheumatoid arthritis, respectively, were included in this study. DNA from synovial fluid of affected knee joints was isolated by QiaAmp-kit (Qiagen, Hilden, Germany) using an adapted protocol. PCRs specific for the 16S rRNA genes of these bacteria were developed. For positive control of DNA preparation the samples were spiked with E.coli strain XL2B. Subgingival bacterial colonization was analysed using micro-Ident® test (HAIN-Diagnostik, Nehren, Germany).
Results: The PCR was optimized in order to detect up to 10 DNA copies of each periodontopathogen. DNA of 2 periodontophatogens, A.a. and P.g., was detected in synovial fluids of two different patients suffering from both juvenile idiopathic arthritis and periodontitis. In the same patients a subgingival infection with P.g. but not A.a. could be detected.
Conclusions: For the first time a highly sensitive molecular based detection system was adapted for the identification of periodontopathogens in synovial fluid. The application of this method allows a better understanding of the interaction of periodontitis and rheumatic diseases. The revealed first results indicate that periodontopathogens may play a role in the pathway of rheumatic diseases.

Schlagwörter: periodontitis, rheumatic disease, periodontopathic bacteria

Konferenz/Veranstaltung:
08.04.2008-10.04.2008
19. Jahrestagung der Deutschen Gesellschaft für Humangenetik
Hannover; Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 391,  Sprache: Englisch
Retention performance of magnetic attachments on dental implants
Boeckler, Arne F./Ehring, Carolin/Setz, Jürgen M.

Introduction: Considering the problem of stabilization of removable prostheses dental mag-netic systems (DMS) offer an alternative to traditional methods. Regarding the technological advantages during the last years DMS have been developed that promise an increase of retentive force by small type of construction. Two physical principles are used: mono-systems with open (MO) and with closed magnetic loops (MC). Furthermore, there are 3 de-signs of keepers for retained roots: prefabricated dowelretained keepers (PK), individual caps of magnetic alloys (IC) and preformed magnets cast on caps of conventional alloys (CC).The aim of this study was to evaluate and to compare the mechanical performance of contemporary DMS used on tooth roots.
Methods: 11 different DMS were standardized tested for maximal retentive force and dynamical development during draw off in an adjusted computer-navigated test-machine (v=20mm/s, s=40mm). From IC/CC-systems root-attachments were produced according to the manufacturers' instructions. 5 specimens of each product were investigated. Denture-magnets and the corresponding keepers or caps were fixed in an individual non-magnetic construction. The results were descriptively and statistically analysed (H-/U-Test). The findings were compared with the manufacturers' statements.
Results: The maximum retentive force ranged from 6,58N to 1,38N. Compared to the manufacturers' information significantly lower initial retention forces were found in all specimens (p0.05). MC showed the highest and MO the lowest initial retention forces. This relation changed with an increasing gap between root and magnet. Considering the different heights and diameters of the products no significant differences were found among the PK-, IC- and CC-systems.
Conclusion: In all products maximum retention forces were found no-table under the manufacturers' information. There were significant differences between the clinically important draw-off forces, whereas no differences between the rootkeeper-designs were found. These results could be useful by individual choice of DMS on retained tooth roots.

Schlagwörter: magnets, keeper, retention, overdentures, attachments

Konferenz/Veranstaltung:
March 9-12, 2005
83rd General Session & Exhibition of the IADR
Baltimore, Maryland, USA

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 397,  Sprache: Englisch
Dental magnetic systems as prosthetic attachments on retained roots
Ehring, Carolin/Boeckler, Arne F./Setz, Jürgen M.

Introduction: Considering the problem of stabilization of removable prostheses dental mag-netic systems (DMS) offer an alternative to traditional methods. Regarding the technological advantages during the last years DMS have been developed that promise an increase of retentive force by small type of construction. Two physical principles are used: mono-systems with open (MO) and with closed magnetic loops (MC). Furthermore, there are 3 de-signs of keepers for retained roots: prefabricated dowelretained keepers (PK), individual caps of magnetic alloys (IC) and preformed magnets cast on caps of conventional alloys (CC).The aim of this study was to evaluate and to compare the mechanical performance of contemporary DMS used on tooth roots.
Methods: 11 different DMS were standardized tested for maximal retentive force and dynamical development during draw off in an adjusted computer-navigated test-machine (v=20mm/s, s=40mm). From IC/CC-systems root-attachments were produced according to the manufacturers' instructions. 5 specimens of each product were investigated. Denture-magnets and the corresponding keepers or caps were fixed in an individual non-magnetic construction. The results were descriptively and statistically analysed (H-/U-Test). The findings were compared with the manufacturers' statements.
Results: The maximum retentive force ranged from 6,58N to 1,38N. Compared to the manufacturers' information significantly lower initial retention forces were found in all specimens (p0.05). MC showed the highest and MO the lowest initial retention forces. This relation changed with an increasing gap between root and magnet. Considering the different heights and diameters of the products no significant differences were found among the PK-, IC- and CC-systems.
Conclusion: In all products maximum retention forces were found no-table under the manufacturers' information. There were significant differences between the clinically important draw-off forces, whereas no differences between the rootkeeper-designs were found. These results could be useful by individual choice of DMS on retained tooth roots.

Schlagwörter: magnets, keeper, retention, overdentures, attachments

Konferenz/Veranstaltung:
March 9-12, 2005
83rd General Session & Exhibition of the IADR
Baltimore, Maryland, USA

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 357,  Sprache: Englisch
A radiographic evaluation of apical root resorption following intrusion therapy
Steffen, Wibke/Röhling, Johannes/Schwestka-Polly, Rainer

Aim: The aim of the present study was to evaluate whether patients treated with an additional upper utility arch show higher amounts of root resorption than patients treated with a straight-wire technique.
Materials and methods: 67 patients were included in this study. 29 of them (group 1) were treated with an additional maxillary utility arch within the straight-wire therapy (intrusion 15gm). 38 patients (group 2) were treated with a straight-wire fixed appliance. The amount of apical root resorption of the maxillary central incisors was determined for each patient by subtracting the post-treatment tooth length from the pre-treatment tooth length measured directly on cephalograms.
Results: Root shortening of the maxillary central incisors was found to average 1,7mm after using an additional maxillary utility arch (group 1) for 5 months (average) and a treatment time of 23,8 months. Root shortening was found to average 0,7 mm after a treatment time of 19,8 months (average). The amount of root resorption between the two orthodontic techniques was compared by means of the student-t-test, showing to be significant.
Conclusion: In the present study, it was found that intrusion with the utility arch type of technique increases the amount of root resorption for the central maxillary incisors. The average amount of root resorption in both groups show no clinical relevance.

Schlagwörter: apical root resorption, intrusion, maxillary central incisor, cephalogram

Konferenz/Veranstaltung:
03.06.-07.06.2005
81st Congress of the European Orthodontic Society
Amsterdam, The Netherlands

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 334,  Sprache: Englisch
Finite Element Simulation of the Human Mandible: The Influence of the PDL on its Structural Behaviour
Kober, Cornelia/Stübinger, Stefan/Erdmann, Bodo/Hellmich, Christian/Radtke, Thomas/Sader, Robert/Zeilhofer, Hans-Florian

Being part of a detailed research project concerning the structural behaviour of a human mandible this paper concerns the influence of the periodontal ligament (PDL) on the structural behaviour of the entire mandible. In the field of implant dentistry, the simulation results provide a comparison of the physiological situation (natural teeth) and the changes due to dental implants.

Schlagwörter: human mandible, biomechanics, finite element simulation, periodontal ligament, adaptation of bone

Konferenz/Veranstaltung:
4./5. November 2005
Das Mundhöhlenkarzinom. Bewährte Konzepte - Moderne Strategien.
20. Jahrestagung der Schweizerischen Gesellschaft für Kiefer- und Gesichtschirurgie
Le carcinome de la cavité buccale. Conceptions eprouvées - Stratégies modernes
Basel, Switzerland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 339,  Sprache: Englisch
Is the genetic background of the proinflammatory cytokine TNF-α a predictor for the development of aggressive and/or chronic periodontitis?
Schulz, Susanne/Machulla, Helmut/Klapproth, Jana/Zimmermann, Uta/Schaller, Hans-Günter/Altermann, Wolfgang/Reichert, Stefan

Periodontitis is a chronic inflammatory disorder of the periodontal supporting tissue of teeth. That's why several factors of the immune response and their genetic background have been proposed as potential markers for the development of this disease. However, existing data are very inconsistent. Therefore, the aim of the present study was to evaluate the importance of genomic variants of the potent proinflammatory cytokine TNF-a for the incidence of chronic and aggressive periodontitis. Methods: In the present study 66 periodontitis patients (chronic: n=34, mean age: 47+10.1y, 38.2% males; aggressive: n=32, mean age: 36.6+7.3y, 40.6% males) and 32 control probands without periodontitis (mean age: 41.6+10.3y, 40.6% males) were included. We investigated genotype, allele and haplotype frequencies of the TNFα-SNP -308G>A and -238G>A by use of PCR-SSP (CTS). Results: Hardy-Weinberg criteria were fulfilled for both SNPs in the patient groups. Investigating genotype and allele frequencies of both SNPs no significant disease specific differences could be detected in comparison with healthy controls. However, in the control group a distinct increase in the prevalence of the mutant genotypes (-308G>A: AG+AA; -238G>A: AG) and alleles (-308G>A: A, -238G>A: A), respectively could be described comparing with patients with chronic (-308G>A: 84.8%, -238G>A: 24.4%) and aggressive periodontitis (-308G>A: 39%, -238G>A: 133%). Compared with chronic (p=0.047), aggressive (p=0.024) and total patient group (p=0.015) in the control group a significant increase in carriers of the mutant haplotypes (haplotypes containing mutant A-allele vs. wildtype GG-GG) could be observed. Conclusions: The significant higher prevalence of carriers of the mutant haplotypes in the control group could be an indication for an altered, possibly more effective immune response to periodontal pathogens since these SNPs were considered to trigger the TNF-a production.

Schlagwörter: TNF-alpha, haplotype, aggressive periodontitis, chronic periodontitis

Konferenz/Veranstaltung:
8.-11.03.2006
17. Tagung der Deutschen Gesellschaft für Humangenetik
Heidelberg

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 257,  Sprache: Deutsch
Faktoren der lokalen Immunabwehr im Speichel im Zusammenhang mit Karies
Juranek, Brigitta/Winkler, Octavia/Hadnagy, Wolfgang/Idel, Helga

The ethiology and pathogenesis of caries are multifactorial in which the local immune defence of the oral cavity plays a pivotal role. In this context the participation of cytokines may be important in the regulation of local immune reactions. The aim of the present study was to investigate the relation between cytokines in saliva and caries.
Unstimulated saliva was obtained from 58 children (33 female, 25 male) aged 8-10 years in the frame of a dental examination. The caries incidence was 44,8 % (26 children). The cytokines determined were interleukin-8 (IL-8), interleukin-1 beta (IL-1 beta) and tumour necrosis factor alpha (TNF alpha). In addition the soluble tumour necrosis factor receptor II (sTNF RIl) and the complement component C3a were measured. The concentrations of all saliva parameters were measured by enzyme-linked immunosorbent assays (ELISA).
The concentrations of examined saliva parameters showed great interindividual variability, however mean values of children with caries showed higher values being significantly for IL-8. Correlations between the cytokines were significantly positive for children with or without caries. Oral hygiene and kind of filling material (plastic fillings) showed significant negative correlations with sTNF RII and TNF alpha, respectively. For IL-8 a significant positive correlation was found in relation to caries.
The increased concentrations of factors of the local immune defence in saliva of children with caries indicate an enhanced local immune activity within the oral cavity. According to the positive association between the chemoattractant IL-8 and caries it is assumed that IL-8 plays a role in the development and progression of caries.

Schlagwörter: saliva, cytokines, caries, Speichel, Zytokine, Karies

Konferenz/Veranstaltung:
28. September - 1. Oktober 2003,
Gemeinsame Tagung der Gesellschaft für Hygiene und Umweltmedizin (GHU) und der
International Society of Environmental Medicine (ISEM),
Tübingen, Deutschland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 266,  Sprache: Deutsch
Die Fibrinmembran als Scaffold für ein rein autologes Bone Tissue Engineering
Nolting, Tim/Szuwart, Thomsas/Wiesmann, Hans-Peter/Joos, Ulrich/Kleinheinz, Johannes

Autologous bone tissue engineering is aimung at the extracorporal rebuilding of lost bone using exclusively cells and matrix from the receiver organism which were manufactured, cultivated and combined in vitro. The aim of this study was to establish a autologous carrier matrix for cells and proteines consisting of fibrin and to characterize the properties of this 100% autologous construction in vitro and in vivo.
Eight minipigs were used for manufacturing of the bone substitute using osteoblasts from the calvarian periosteum and endothelial cells from the jugular vein. Cells were cultivated until confluent stage and then seeded on a fibrin matrix based on autologous blood serum, combined with a autologous platelet-rich-plasma-concentrate and replantet in a critical size defect of the mandible. Specimens were taken at day 7 and 14 and analysed. Simultaneous attachment, proliferation, and differentiation of the cells on the carrier matrix was evaluated.
In vitro results demonstrated complete attachment of the cells on the matrix surface after 6 hours and distinctive proliferation of both cell types after 48 hours without any apoptotic signs. In 6 of the 8 animals histomorphometric analyses revealed an accelerated bone regeneration. Immunohistologic staining for endothelial cells showed an increased angiogenic front within the fibrin matrix, which was clearly in front of the osteogenic front. With the help of cell tracking technique it was possible to identify the transplanted cells over the whole period of investigation.
With this study we could demonstrate the possibility of creating a total autologous bone substitute. Based on vital transplanted cells and the nature of the matrix this construction is able to regenerate a bony defect in a fast and reliable manner.

Schlagwörter: Autologes Tissue Engineering, Fibrin, Endothelzellen, Osteoblasten, Autologous tissue engineering, fibrin, endothelial cells, osteoblasts

Poster Award: DGZMK/Dentsply/BZÄK Förderpreis

Konferenz/Veranstaltung:
30.09.2004 - 02.10.2004
128. Jahrestagung der Deutschen Gesellschaft für Zahn-, Mund- und Kieferheilkunde
Stuttgart, Deutschland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 226,  Sprache: Englisch
Pulp fibroblasts and dental materials - an In-vitro-study
Korneli, Nicole/Preußker, Susann/Klimm, Wolfgang

The purpose of this study was to test the viability of human pulp fibroblasts on certain dental materials after their direct application. the materials tested were: Dycal®, Calxyl®, a calcium hydroxide-suspension (0.001137g Calxyl®/ml medium), zinc oxide-eugenol, the glassionomer cement Ketac-Molar® Aplicap® and the dentin adhesive OptiBond SoloTM. At first we used all materials in a 96well assay and then we repeat the study in a 24well assay with the calcium hydroxide-containing materials only. To measure the viability, the viability test EZ4U was carried out in the two assays after 3, 6, 12, 24, 48 hours and 4, 8, 16 and 32 days. The result of both assays suggest, that the direct application of aqueous calcium hydroxide-suspensions will show the lowest decrease in viability of human pulp fibroblasts.

Schlagwörter: pulp, fibroblasts, cells, cultured, biocompatibility, dental materials

Konferenz/Veranstaltung:
October, 3-5th, 2002
126. Jahrestagung der DGZMK
Hannover/Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 215,  Sprache: Englisch
Age Threshold for the Association of Periodontitis with Ischemic Stroke
Dörfer, Christof E./Kaiser, Claudia/Becher, Heiko/Buggle, Florian/Lichy, Christoph/Ziegler, Christoph

Aim of this study was to investigate the influence of the age of a study population on the association between periodontitis and ischemic stroke. Methods: 303 consecutive patients with acute ischemic stroke (T) and 300 representative population controls (C) matched for age, gender and area of resi-dence were divided into subjects with a maximum age of 60y (T: 144, C:159; group I) and those, who were older (T:159, C:141, group II). Subjects were clinically and radiographically examined for the presence of periodontitis. A questionnaire was used by trained interviewers in a face-to-face in-terview to investigate all known and/or suspected risk factors for stroke and periodontitis. Results: In group I, stroke patients showed statistically significant higher attachment loss (CAL; T: 4.0 ± 1.3 mm; C: 3.5 ± 0.8mm). There was no statistically significant difference in group II (T: 4.6 ± 1.4mm; C: 4.3 ± 1.4mm). After correction for age, gender and tooth loss, in group I a CAL of >4mm (OR 7.52; 95%-CI 2.77-20.39; p 4mm (7.40; 95%-CI 2.36-23.23; p=0.001) remained a significant risk factor. In group II in neither model any statistically significant association could be detected. Conclusion: As-sociations between periodontitis and cerebrovascular disease seem to be detectable in younger pa-tients, only. This study was funded by The German Research Council (DFG Grant# Gr1102/3-1)

Schlagwörter: periodontitis, ischemic stroke, cerebrovascular disease

Konferenz/Veranstaltung:
September 25-28th, 2002
Jahrestagung der CED
Cardiff/Great Britain

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 194,  Sprache: Englisch
Treatment of gustatory sweating with botulinum toxin: A prospective study on long-term efficiacy and quality of life
Eulzer, Christopher/Teltzrow, Thomas/Küttner, Christian

Introduction: Gustatory sweating is a common complication of parotid gland surgery. Botulinum toxin A (BTX) is considered being effective. This study was designed to evaluate the efficacy on long-term and to value quality of life.
Method: Seventeen patients with severe gustatory sweating were treated with injections of one unit/cm2 BTX intracutaneously. The evaluation relied on self-assesment of patients and on clinical examinations four weeks, four, eight, twelve and eigtheen month after treatment. Minor's test was performed and digital photograph aided to calculate affected skin area. Quality of life was evaluated by SF-36 before, six and eighteen month after treatment.
Results: The efficiacy of BTX was exellent in the facial skin and less effective in hairy temporal region. Overall there was a median reduction of affected skin area from 30 cm2 to less than 2 cm2. Within eighteen month seven patients (41%) had a symptomatic recurrent gustatory sweating, five patients had an increase in Minor's test without clinical relevance and five patients had no signs of recurrent sweating at all. The overall data have shown an increase in affected skin over eigtheen month, but no significant changes (p=0.117). Quality of life increased over the time. Significant levels could be seen in 'Mental Health' and 'Social Function'.
Conclusion: BTX has proven to be a save and highly effective in treatment of gustatory sweating which improves quality of life. 60% of the patients had an asymtomatic period of at least eighteen month.

Schlagwörter: botulinum toxin, gustatory sweating, Frey's syndrome

Konferenz/Veranstaltung:
8. bis 12. Juni 2002
International Conference 2002: Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins
Hannover, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 124,  Sprache: Englisch
Quality of life of head and neck cancer patients during and after therapy
Hertrampf, Katrin/Wenz, Hans-Jürgen/Koller, Michael/Lorenz, Wilfried/Lehmann, Klaus M.

The management of head and neck cancer patients is a multidisciplinary approach. Especially patients with persisting maxillofacial defects after surgery experience a restriction of their quality of life during and after therapy. The evaluation of quality of life has become an important aspect in the medical treatment of cancer patients. In dentistry, however, only few information is available how head and neck cancer patients feel during and after therapy.The purpose of this study was to investigate how cancer patients with maxillofacial defects (experimental group) evaluate their quality of life compared to a non-tumour control group with multiple teeth extractions. It is known that patients with a long history of medical treatment adapt to their specific situation (coping phenomenon) and that differences in the global quality of life in comparison with a control group are difficult to detect. So additionally, changes in quality of life during the multidisciplinary therapy were assessed retrospectively.A total of 34 patients were included in the study, 17 in each group. All patients completed their therapy including prosthetic rehabilitation between 1995 and 1999. Global quality of life was measured with a standardized questionnaire (EORTC QLQ C-30). In addition, the patients were interviewed in a standardized format to obtain their retrospective views of quality of life during therapy.At the time of investigation, no significant differences in quality of life were found between both groups but the interview revealed differences in the retrospective evaluation of quality of life. Especially diagnosis, but also surgery and radiotherapy were the most incriminating periods of the therapy for the head an neck cancer patients. The results indicate that these patients need psychological support which should start with the diagnosis and should at least proceed throughout the radiation therapy.

Schlagwörter: quality of life, patients with maxillofacial defects, interview

Konferenz/Veranstaltung:
06.-08-09.2001
EPA (European Prosthodontic Association)
Prag, Tschechien

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 64,  Sprache: Englisch
RH 414 a New Dye to stain non - Decalcified Bone Tissue
Meyle, Joerg/Knoblauch, Michael/Roessler, Ralf/Anil, Ata

Histological analysis of hard tissue is hampered by the fact that embedding in methacrylate reduces the spectrum for staining and labelling using monoclonal antibodies. It was the aim of this study to develop a new technique of sample preparation and histological analysis using confocal laser scanning microscopy (CLSM).Bone samples from the medial cortex of proximal tibiae of 3 dogs were removed during implant surgery and fixed in 4% formaldehyde for histological analysis. The material was divided into 4 pieces of similar size, the formaldeyde was removed, subsequently the specimens were stained for 24 h using RH 414 or DiOC 6/7 (Molecular Probes), which have been used for membrane labelling. The stained bone samples were analyzed in the Leica TCS 4D confocal laser scanning microscope (CLSM). Then they were embedded in paraffin or in laromin C 268 (BASF, Ludwigshafen) and thinned by grinding (Donath, 1982) for parallel analysis using CLSM, light (LM) and fluorescence microscopy (FM).Bone cells with their typical morphology could easily be identified by LM and CLSM, but not by FM. Cellular elements were still visible even when the focal plane was adjusted 60 µm below the sample surface. Optical sections in x/z-direction revealed cells even 100 µm below the surface irrespective of the mode of sample preparation. The newly developed technique allows microscopic analysis of cellular elements on the surface and below the surface without decalcification of the bone sample.

Konferenz/Veranstaltung:
10.03.99-10.03.99
77th General Session of the IADR
Vancouver, Canada

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 55,  Sprache: Englisch
New Aspects concerning X-ray Protection - Dose Reduction versus Diagnostic Information?
Segerath, Catrin/Stamm, Thomas/Renger, Bernhard/Ehmer, Ulrike/Heindel, Walter L.

In comparison to conventional screen-film combinations Digital Radiography (DR) offers several advantages, i.e. reduction of the x-ray exposure and the further option of image processing. It is an obvious controversy that collimated film areas provide information for cephalometric analyses. One of the most interesting side effects of DR is the possibility to perform a complete analysis of the entire scull in typically collimated lateral cephalograms.The aim of this prospective study was to determine the validity of this special image processing method developed by the Department of Orthodontics, University of Muenster.Out of 400 digital radiographs taken for orthodontic diagnosis, 100 lateral head films were randomly selected. The routine radiographs were taken from the Department of Radiology, University of Muenster. For each patient the facial cranium exclusively was faded in and exposed at 77kV/12 mAs with an anode to film distance of 350 cm.The digital image acquisition included laser-scanning (pre-read) of the storage phosphor plates, individual processing of every image (Pattern Recognition for Iris of Exposure Field - algorithm) and storing of the original and processed images using the DICOM - format.The intra-individual reproducibility of the landmarks defined by DELAIRE who proposed a cranial and craniofacial analysis was examined using the NIH-Image 1.62 analysis program.The results show that it is possible to attain information from collimated areas (cranial vault, cervical vertebra) using DR combined with special image processing methods. This is due to the x-ray scatter and the various contrast enhancements possible in different film areas of the same image.The information attained from these areas with very low x-ray load is sufficient for a complete cranial analysis proposed by DELAIRE, so that an increase of field size can be avoided in many clinical cases.For the first time since 1987 the gold standard of head film acquisition for the DELAIRE-Analysis proposed by PRECIOUS and MILES has been redefined.

Schlagwörter: Digitale Fernröntgenseitenbilder, digitale Lumineszenzradiographie,Strahlenreduktion, Delaire-Analyse

Poster Award: Posterpreis

Konferenz/Veranstaltung:
30.09.99-02.10.99
123. Jahrestagung der DGZMK und Ihrer Akademie Praxis und Wissenschaft,
50. Jahrestagung der Arbeitsgemeinschaft Kieferchirurgie,
21. Jahrestagung des Arbeitskreises Oralpathologie und Oralmedizin,
Maritim Congress Centrum Bonn

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 12,  Sprache: Englisch
Unilateral loss of occlusal support during deciduous dentition and its consequences to the growing mandibular condyle.
Springer, Ingo/Fleiner, Bernd

Loss of supporting zones during deciduous dentition effects the condylar growth and the spongybone density of the mandibular condyle. This is a quantitativeanalysis. The deciduous molars of micropigs are removed unilaterally. Sequence fluorochrome labeling is performed during the four month course of experiment.The examination is done on non-decalcified serial sagittal sections of the TMJ. The condyles of the distracted joints show a higher growth-rate compared to theextraction-side condyles, resulting in an 1.56 (p=0.003) times thicker additional vertical bone layer. This factor is ventral higher than dorsal (p=0.0311), increasing at the most from dorsomedial (1.33) to ventrolateral (2.38), which implies a reciprocal change of the condylar surface curve. However, the higher condylar growth of the unloaded condyles is correlated to a lower density of the corresponding subchondral spongy bone (7.38% difference, p=0.002). The total amount of bone produced is 1.33 times higher on the unloaded side. Aside with adaptive changes degenerative changes occur as well. So, for the first time the influence of unilateral loss of occlusal support on the mandibular condyles vertical growth, its trabecular bone volume and its amount of mineralized bone-matrix generated is quantified. Unilateral loss of occlusal support during deciduous dentition may lead to undesired adaptive and degenerative changes of the TMJ.

Schlagwörter: occlusal-support, unilateral-loss, quantification, condylar-growth, condylar-shape, subchondral-spongy-bone-density, degenerative-changes

Konferenz/Veranstaltung:
15.10.98-17.10.98
122. Jahrestagung der DGZMK gemeinsam mit der 12. Jahrestagung der Deutschen Gesellschaft für Zahnerhaltung
Maritim Congress Centrum Bremen

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 649,  Sprache: Englisch
Salivary Biosensors: Diagnosing the Nano-Way
Mahima, Guledgud V. / Patil, Karthikeya / Verma, Saumya

As we approach the dawn of genomic medicine, the escalating use of salivary diagnostics will help spur a shift from disease diagnosis to real-time health surveillance. With newly evolving technologies like the biosensors its becoming progressively easy to detect minute quantities of salivary components including mRNA , proteins , cortisol , and others. The domain of salivary diagnostics via salivary biosensors has catapulted into one of dentistry's most promising areas of research. Because of non-invasive nature of salivary collection, point-of-care diagnostics is set to become the Holy Grail for healthcare in 21st century. Coupling this with devices being developed in nanotechnology, we are about to realize portable devices that can revolutionalize the diagnosis of a wide variety of disease conditions on site using an oral sample. A salivary biosensor is a small, self-contained device which utilizes biological reactions for detecting and measuring a particular substance [a salivary biomarker] of interest. The biosensor consists of a biological recognition element in intimate contact with a transducer that translates the bio-recognition event into a useful electrical signal. The commonly used transducers include optical, electrochemical or mass-sensitive elements and generate light, current or frequency signals, respectively. The advantages of using biosensor in salivary diagnostics are that it eliminates the need for a trained technician and also eliminates the risk of contracting infectious disease for both technician and patient. Moreover, it offers detection of malignancies at a sufficiently early stage, and also has implications in bioterrorism surveillance.

Schlagwörter: Saliva, biosensors, biomarkers, genomics

Konferenz/Veranstaltung:
july 23rd-24th, 2011
National Triple "O" Symposium on Salivary gland disorders: Recent advances in diagnosis and management
Raipur, Chattisgarh, India

 Abstract ein-/ausblenden      Volltext (pdf)      Poster Image (jpg)

Poster 636,  Sprache: Englisch
Inter-operator reliability of overlay generation techniques in bite mark analysis
Khatri, Mihir / Mariappan, Jonathan Daniel

Overlays are representative of incisal edges of the teeth produced over transparent sheet. They are used most commonly for comparison of bite mark pattern of a suspect with that found on an animate or inanimate object. There are many techniques of overlay generation like the manual, photocopying and computer assisted techniques. With this background a study was conducted to evaluate various overlay generation techniques and to evaluate the inter-operator reliability in comparing the overlays generated. Overlay production was done by manual, photocopying and computer assisted techniques. As two examiners conducted the observation in our study, we were able to find the inter-operator reliability of the overlays generated. The computer assisted overlays were found to give reliable results.

Schlagwörter: Inter-operator reliability, manual, photocopying, computer assisted technique, Photoshop software version 7, magical wand selection tool

Poster Award: 2nd best poster award

Konferenz/Veranstaltung:
8th to 11th December, 2011.
23rd National Conference of Indian Academy of Oral Medicine and Radiology
Bengaluru, Karnataka, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 599,  Sprache: Deutsch
Klinische Studie zur Evaluierung eines qualitativen aMMP-8 Chairside Tests
Lorenz, Katrin / Bruhn, Gerlinde / Freitag, Anne / Netuschil, Lutz / Hoffmann, Thomas

Aim: Numerous investigations have found active metallomatrix proteinase 8 (aMMP-8) to be a relevant inflammatory marker for early stages of periodontal tissue destruction. The first chairside aMMP-8 test just recently entered the market. It was the aim of this prospective, monocenter case-control study to compare the diagnostic accuracy of this chairside test (PerioMarker® aMMP-8 Schnelltest von Chlorhexamed®) with the conventional laboratory method (ELISA).
Methods: For this study, 35 periodontally healthy participants, 60 patients who had gingivitis, and 35 periodontitis patients were recruited. In order to differentiate between the groups, the periodontal screening index was applied. Primary variable was the aMMP-8 chairside test result. Secondary variables were aMMP-8 ELISA test results, plaque index, gingivitis index, bleeding on probing, periodontal pocket depths, clinical attachment level. Parameters were recorded at baseline and after therapy. Healthy participants did not receive any therapy; parameter recording took place at baseline and after four weeks. Gingivitis patients received a dental prophylaxis, periodontitis patients received a deep scaling. Both patient groups were recalled 12 weeks after baseline. Positive and negative agreement [%] between test and control methods was calculated as measure of diagnostic accuracy. The agreement between aMMP-8 concentrations and clinical parameters before and after therapy was assessed by means of contingency tables.
Results: Positive agreement between both aMMP-8 methods was found in 75.8% (95%-CI 57.7 - 88.9%). Negative agreement was found in 92.8% (95%-CI: 85.7% - 97.0%). In total, the agreement of test results was kappa=0.692 before therapy and kappa=0.693 after therapy. The percentage of positive test results increased strongly from healthy participants to periodontitis patients.
Conclusion: The chairside aMMP-8 test is as exact as ELISA to detect increased MMP-8 activity in patients who have gingivitis and periodontitis. Negative test results indicate healthy periodontal conditions.

Schlagwörter: biomarker, aMMP8, parodontitis, chairside test

Poster Award: 2. Posterpreis

Konferenz/Veranstaltung:
15.-17. September 2011
DGP Jahrestagung
Baden-Baden

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 577,  Sprache: Deutsch
Der Einfluss von zwei Desensitizern auf die Scherfestigkeiten von Keramiken auf Dentin
Bekes, Katrin / Brandt, Karolin / Scholz, Petra / Schaller, Hans-Günter / Gernhardt, Christian Ralf

Objective: The aim of the present study was to evaluate the influence of desensitizer application (Hyposen, Lege Artis and Gluma Desensitizer, Heraeus Kulzer) on shear bond strength of ceramics to dentin.
Material and methods: 72 freshly extracted third molars were included. Standardized cervical dentin specimens were prepared allowing the simulation of dentin perfusion. The specimens were divided at random into six experimental groups: Group VC: no desensitizer/ Variolink II; Group VH: Hyposen/ Variolink II; Group VG: Gluma/ Variolink II; Group BC: no desensitizer/ Bifix SE; Group BH: Hyposen/ Bifix SE; Group BG: Gluma/ Bifix SE. The desensitizers and adhesive cements were applied as recommended by the manufacturer. Shear bond strength of the above mentioned adhesive cements with or without desensitizer application to ceramic (IPS Empress, Ivoclar Vivadent) was measured using a special device in a universal testing machine.
Results: The following shear bond strengths were obtained (mean values and standard deviations in MPa): Group VC: 5.56 ± 0.61, Group VH: 5.28 ± 0.96, Group VG: 3.04 ± 0.18, Group BC: 3.60 ± 1.38, Group BH: 3.60 ± 1.36, Group BG: 2.06 ± 0.16. Statistical analysis showed a significant influence of the used desensitizer and adhesive cement on shear bond strength (ANOVA). Treatment with Gluma (VG, BG) resulted in significantly lower bond strength values (p<0.001; Tukey's Test). Pairwise comparison between the adhesive cements showed significantly higher values for Variolink II (p<0.001; Tukey's Test). Within the limitations of an in vitro investigation it can be concluded that the application of desensitizers reduce the shear bond strength of all tested adhesive systems.

Schlagwörter: adhesives, ceramics, desensitizer, resin cements, shear bond strength

Poster Award: Jahresbestpreis der Deutschen Gesellschaft für Zahnerhaltungskunde (3. Platz Poster)

Konferenz/Veranstaltung:
10.-13.11.2010
Deutscher Zahnärztetag 2010
Frankfurt am Main

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 582,  Sprache: Englisch
Constriction with Conviction
Patni, Pallav Mahesh / Manoj, Chandak / Ghonmode, W. N. / Amit, Heda / Patni Mona, Jain

Caries detector dyes are used to help you distinguish between affected and infected dentin. Affected dentin is not infused with bacteria, and even though it might be softer than what we usually consider to be good, sound, hard dentin, should not be removed, while infected dentin must be removed before restoring the cavity. The dye evidently works by bonding to denatured collagen in the dentin, which is a byproduct of the decay process. They also help identify cracks and the location of even partially calcified pulpal tissue as an aid in canal identification for endodontic treatment.

Schlagwörter: caries detection, dyes, tooth conservation

Poster Award: Silver

Konferenz/Veranstaltung:
25th-27th June 2004
5th All India P.G Students Convention, Conservative Dentistry and Endodontics.
Kanyakumari, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 588,  Sprache: Englisch
Stem Cells - A new Generation of Regeneration
Garima, Makked / Kumar, C. Anand

Stem cells are the class of undifferentiated cells that are able to differentiate into any specialized cell type. Teeth contain a rich source of highly potent stem cells which can be easily collected & stored for future medical & dental use. Tooth loss or absence is a common & frequent situation that can result from numerous pathologies such as periodontal diseases, dental caries, fractures, injuries and genetic alterations. For aesthetical, psychological & medical reasons, replacement of missing teeth is important. Modern dentistry for replacing missing teeth utilizes advances in stem cell biology. Emerging concepts in tissue engineering i.e. biological teeth may become an alternative for replacing missing teeth. This poster presents the idea to cultivate stem cells with odontogenic induction through epithelial - mesenchymal interaction, to adopt dental lineages with the help of scaffold /extracellular matrix to become a part of the tooth.

Schlagwörter: stem cell, tissue engineering, tooth regeneration

Poster Award: 1st Best Poster Prize

Konferenz/Veranstaltung:
1st & 2nd August, 2009
National Indian Academy of Oral Medicine & Radiology Post Graduate Convention 2009
Campus Auditorium, K.D.Dental College & Hospital Campus, Mathura, Uttar Pradesh, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 555,  Sprache: Englisch
A New Dental Material for Remineralisation of Caries Lesion Used as a Root Canal Sealer
Mustafa, Ammar A. / Al-Khateeb, Khalid A. S. / Ismail, Ahmad Faris

Two experimental GIC-based root canal ‎sealers were prepared for the purpose of the ‎study with a main formula of boro-tri-fluoro-‎alumino-silicate (BTFAS) for the test-1 and ‎strontium fluoride SrF2 for test-2. Ninety ‎specimens of human sound teeth were embedded ‎into an acrylic mould. A conventional root canal ‎preparation without root canal filling was ‎performed. After sectioning the teeth ‎longitudinally, the internal side of the canal was ‎subjected to a demineralising solution to produce ‎a caries-like lesion. After the end of each ‎demineralizing period, the specimens were ‎examined under transversal micro-radiography ‎to have the (control radiographs). Then a film ‎layer of the experimental sealer test-1 was applied ‎to half of the specimens (n=45) and another film ‎of experimental sealer test-2 was applied to the ‎rest of the specimens (n=45). The test specimens ‎were divided into three time groups to be re-‎evaluated by transversal micro-radiography (test-‎radiographs) after 14 days, 28 days, and two ‎months. The specimens were further sectioned ‎and examined under SEM to support the ‎findings of transversal radio-micrograph. The ‎results illustrate a significant difference between ‎the two months test group and the control ‎radiographs but with no significant differences ‎among the other groups. It was obvious that the ‎secondary canals were ‎changed in texture which may be attributed to ‎precipitation of mineral ions by the glass Ionomer ‎sealer. The study needs further investigations to ‎prove the research hypothesis. ‎

Schlagwörter: glass ionomer cement, remineralization, root canal sealer, secondary canals, demineralization

Poster Award: Silver Medal

Konferenz/Veranstaltung:
17-19 February 2011
Malaysian Technology Expo MTE 2011, an International Expo on Technology, Invention & Innovation
Kuala Lumpur, Malaysia

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 567,  Sprache: Englisch
Hot shots - Thermographic imaging
Pramod, Gujjar Vittoba Rao / Lele, Shailesh / Sujata, G. P.

The normal internal temperature in resting man is maintained within very narrow limits, inspite of wide variations in the environmental temperature. Under steady state condition heat flows from production site in the body to cooler tissues and blood distributes this heat to the body surface from where it is dissipated to the external environment by radiation, convection and evaporation. The importance of deep body temperature as an indicator of disease has been known for centuries; but in recent years attention has been paid to the significance of skin temperature. So thermography was developed, which is a measuring technique that portray surface temperature distributions pictorially, painlessly and is free of radiation. This is accomplished either with liquid crystals or infrared scanning equipment. This technology lost favour some 20 years ago, but with new ultra sensitive high resolution digital infrared devices, efficacy is much improved. This poster presentation is an attempt to show that modern thermography can also be used as an adjunctive diagnostic and preventive medicine tool.

Schlagwörter: thermogram, infra-red radiation, heat, imaging, temperature, medical thermograpy, oral and maxillo-facial thermography

Poster Award: Best National Paper Presentation

Konferenz/Veranstaltung:
20th-22nd December 2002
14th National Conference of Indian Academy Of Oral Medicine And Radiology
Bangalore, Karnataka State, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 568,  Sprache: Englisch
Dental Caries - An Ever Expanding Horizon
Jahagirdar, Abhishek / Mujib B. R., Ahmed / G. Kulkarni, Pavan

One of the major diseases affecting mankind is caries and pulpal diseases. Dental caries is one which remains a puzzle for the present generation. Dental caries prevention and eradication remains an enigma to researchers and dentists. The combination of genetics, engineering and biotechnology combined with dentistry resulted in a new era of modern dentistry with answers to these mysterious questions. Few researches in their early stages have proven that many latest methods with superior technologies are more effective in prevention, reversal, eradication with minimal intervention in treatment of caries. This poster highlights many future technologies like the Bluetooth device for pH detection and ozone therapy for caries reversal etc.that are under research, which can provide a glistening future to dentistry. The promising answer is that if dental practitioners adapt themselves to the future techniques, "DENTAL CARIES", the hidden enemy can be shrunken in its bud stage.

Schlagwörter: dental caries, caries diagnosis, caries reversal

Poster Award: First Prize

Konferenz/Veranstaltung:
June 16th-17th, 2010
10th National Post Graduate Convention of Indian Association of Oral and Maxillofacial Pathologists
Club Mahindra Holiday Resorts, Coorg, Karnataka, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 569,  Sprache: Englisch
Cyberknife
Soman, Cristalle / Ashok, Lingappa

Cyberknife is a high precision, painless, non-invasive robot guided frameless steriotactic radiosurgery system. It is the first and only radiosurgery system designed for treatment anywhere in the body. Cyberknife uses continual X-ray image guidance technology and computer-controlled robotic mobility to automatically track, detect, and correct for patient movements and target without interrupting the treatment. Cyberknife has proven to be effective alternative to surgery or conventional radiation for treating many conditions like vascular abnormalities-AVM, head and neck tumors, nasal and orbital tumors, cervical tumors, trigeminal neuralgia, pituitary adenomas in sub-millimeter accuracy and provides enhanced ability to avoid critical structures. Cyberknife gives a renewed ray of hope for a better quality of life especially for patients with previously diagnosed inoperable or inaccessible tumors and for those who have already received the maximum amount of radiation through other treatment methods and offers quick recovery and return to normal life.

Schlagwörter: Cyberknife, stereotactic, robotic mobility, sub-millimeter accuracy

Poster Award: Certificate

Konferenz/Veranstaltung:
September 4th-5th, 2010
National P.G Convention in Indian Academy of Oral Medicine and Radiology 2010
Le Meridien,Chennai, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 549,  Sprache: Englisch
Mesiodens in monozygotic male twins, Mesiodens bei monozygoten männlichen Zwillingen
Meißner, Simon / Ebhardt, Harald / Schmidt-Westhausen, Andrea Maria

Case Report: Mesiodens in monozygotic male twins: Diagnosis and surgical therapy.
Introduction: The incidence of supernumerary teeth reported in the literature is 0.15 - 3.9% and it is five times more common in permanent dentition teeth. Mesiodens is defined as a tooth additional to the normal dentition, commonly seen in the maxillary arch, centrally located between the roots of the upper incisors. The overall incidence is 0.15% - 1.9%, with the ratio men to women being 2:1. The aim of this case report is the presentation of diagnostic and surgical treatment of mesiodens, including etiological factors in monozygotic twins.
Clinic: We report on two 10-year-old monozygotic male twins. Evaluation of the DVT in the upper jaw showed a rudimentary, inverted conical mesiodens centrally located between the root apices of teeth 11 and 21, cranially limited by a thin cortical lamina to the nasal floor. Radiographic imaging of the single maxillary anterior region of his twin brother also revealed a mesiodens in the same region. The DVT showed a varied location of the rudimentary, slightly enlarged, inverted and conical mesiodens in the same region, in mirror-symmetrical position relative to the median sagittal plane. Surgical removal of the mesiodens in both twins was performed under local anesthesia, using intrasulcular vestibular incision and minimally invasive osteotomy.
Discussion: The occurrence of mesiodentes in twins is rare, only few case reports depicted in the literature can elucidate the etiology and a presumed genetic component. The absolute incidence of monozygotic twins is 3.5 - 4 per thousand pregnancies and is independent of maternal age or race and is similar in all populations. Regarding the etiologic background, a zygote that divides prior to lateral differentiation will produce identical monozygotic twins. The division of the blastocyst at a later stage can lead to increased levels of asymmetry. The different relationship of twins to each other within the membranes of the placenta has an impact on the respective axial asymmetries. The mirror image of unilateral mesiodentes occurring in twins has been described. An autosomal dominant disorder with incomplete penetrance genes may play a role in the increased incidence among first-degree relatives. Even small differences of epigenetic influences on tooth development may be responsible for differences in the expression in monozygotic twins. So far, several theories have been put forward for the formation of mesiodentes. These include the theories of atavism, the dichotomy / schizodontia, hyperactivity of the dental lamina, family history, asymptomatic autosomal dominant holoprosencephaly and environmental factors such as radiation, and the influence of exogenous epidermal growth factor and vitamin A. Supernumerary teeth may occur in isolation or in combination with syndrome disorders. Complications related to mesiodentes are eruption in the nasal cavity, retention and abnormal root development of permanent front teeth, crowding and development of diastema, as well as the emergence of follicular cyst or keratocystic odontogenic tumour, which may lead to root resorption and rotation of the adjacent teeth. Early diagnosis and treatment is required to avoid complications.
Conclusion: In monozygotic twins with a positive family history of supernumerary tooth germs, a radiological examination of the twin sibling may reveal a similar condition. A DVT is helpful for three-dimensional diagnostics and surgical planning. DVT is an excellent tool for the surgical removal of the mesiodentes in terms of protecting adjacent structures and for deciding whether surgery should be performed before or after the commencement of the completed root development of permanent incisors.

Schlagwörter: mesiodens, monozygotic twins, digital volume tomography, surgical removal

Poster Award: Award for the best poster presentation

Konferenz/Veranstaltung:
June 02.-03., 2011
61. Jahrestagung der Arbeitsgemeinschaft für Kieferchirurgie
Bad Homburg, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 554,  Sprache: Englisch
Ultrasonography - it's revival in dentistry
Vishnuprashad, Aniruddh Yashwant / Agrawal, Arti / Mariappan, Jonathan Daniel

Ultrasonography has been a useful diagnostic tool in dentistry since its inception in 1960s. It is a process that uses the reflection of high-frequency (3 to 10MHz) sound waves to make an image of structures deep within the body. Ultrasound is produced by the vibration of a synthetic crystal that possesses piezoelectric properties. Ultrasound is generated when a rapidly alternating electrical potential causes the crystal to vibrate. When the burst meets an acoustic boundary part of the energy is reflected, this echo is detected by the transducer. By means of the reversed piezoelectric effect the reflected sound waves are transformed by the crystals in the transducer into an electrical signal. The amplitude of the electrical signal is proportional to the acoustic properties of the tissue interface. In the scan converter the amplified signal is converted into a digital signal enabling it to be easily processed and stored.The types of ultrasonography include A-mode ultrasonography, B-mode ultrasonography, Gray-scale ultrasonography, M-mode ultrasonography, Doppler ultrasonography, real time and endoscopic ultrasonography. Technological progress in sonography has made this noninvasive procedure with multiple operating modes the initial imaging technique of choice for the salivary glands and head & neck cancer. Owing to the superficial location of these glands, high-frequency ultrasound transducers provide markedly better spatial resolution than other imaging modalities. Ultrasound can also effectively guide and improve the safety of aspiration biopsy of inflammatory and tumoral lesions. Color doppler allows assessment of salivary gland function and accurate analysis of tumor vascularity. The vascular pattern and displacement of vascularity of the lymph nodes are also assessed using ultrasonography.Metastatic and lymphomatous nodes tend to have sharp borders, whereas reactive and normal nodes usually show unsharp borders. Also, serial change in size of malignant nodes is useful in monitoring patient's response to treatment. Normal, reactive, lymphomatous and tuberculous nodes are predominantly hypoechoic when compared with the adjacent muscles. In cellulitis, well defined hypoechoic septa between fat and connective tissue is seen[characteristic cobblestone appearance] In abscess, anechoic to hyperechoic areas due to sediment, septa or gas may be seen. Ultrasonography is used in the assessment of Temporomandibular joint. Head of the condyle and the articular eminence, is generally hypoechoic ,the margin of the bone is hyperechoic. The joint capsule, retrodiscal tissue,lateral pterygoid and masseter muscles,are isoechoic and appear grey.More recently it has been useful in the diagnosis of fracture of teeth, measurement of enamel thickness and periodontal pocket depth and distraction osteogenesis. Thus ultrasonography is a non-ionizing, non-invasive and relatively inexpensive imaging modality which can be used effectively in maxillofacial imaging.

Schlagwörter: ultrasonography

Poster Award: Award for the best poster

Konferenz/Veranstaltung:
5.12.2010
National BDS students seminar on Oral Medicine and Radiology
Chennai, Tamil Nadu, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 522,  Sprache: Englisch
Electron spin resonance spectroscopy (ESR) of albumin for diagnosis of oral squamous cell carcinoma - a pilot study
Kämmerer, Peer W. / Moergel, Maximilian / Schnurr, Kerstin / Klein, Marcus Oliver / Bemsch, Andreas / Al-Nawas, Bilal

Introduction: Albumin is known to play an important role for transportation of various proteins, peptides and low molecular weight molecules produced by tumor cells. The novel technique of spin labelling followed by electron spin resonance spectroscopy (ESR) is a tool to evaluate the structural and functional changes that can occur to albumin following the binding of various ligands. A difference of albumin functionality between cancer patients and healthy persons has been described in other tumor entities. Therefore, the present study investigated the value of ESR analysis for albumin-bound molecules as a possible biomarker in oral squamous cell carcinoma (OSCC).
Material and Method: ESR was tested blinded to the clinical data. Peripheral blood was isolated from 32 patients with histological verified OSCC (m=18, w=14; T1 n=11, T2 n=10, T3 n=6, T4 n=5; N0 n=24, N1 n=6) and tested against 30 healthy volunteers (age and gender matched). A discriminant variable (DR) was calculated. Obtained data were associated with pathological and clinical data.
Results: The analysis revealed a diagnostic sensitivity in detection of OSCC of 72% (23/32 patients with OSCC) and a specificity of 80% (24/30 healthy volunteers). A sub-group analysis with patients without leucocyte elevation (52 patients (84%; OSCC-group n=23, healthy volunteers n=29) was conducted. Here, sensitivity added up to 87% (20/23), specificity to 83% (24/29). In both groups, DR was significant different (p < 0.001) between OSCC- and volunteer group. ESR measurement "detected" all T4- as well as all N-1 stadiums.
Discussion: High sensitivity and specificity implies a promising approach towards detection of OSCC by peripheral blood analysis. Nevertheless, inflammation seems to be a major confounder. As OSCC is often accompanied with inflammation, the method may be not appropriate in these cases. Prospective studies with higher patient numbers and an optional combination with other biomarkers are needed to confirm the value of ESR in OSCC diagnosis.

Schlagwörter: oral cancer, diagnosis, electron spin resonance, albumin

Poster Award: Poster-Award for the best poster of the congress

Konferenz/Veranstaltung:
25.-29. Mai 2010
60. Kongress der Deutschen Gesellschaft für Mund-, Kiefer- und Gesichtschirurgie
München

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 524,  Sprache: Deutsch
Komplexe kaufunktionelle Rehabilitation einer neurologisch geschädigten Patientin mit Hilfe des BIOMET 3i Encode® Abformsystems
Steck, Florian / Schweizer, Marc / Kehrer, Frank / Jeggle, Ulrich

A mentally retarded patient with reduced physical abilities received five dental implants in different lengths and diameters. These implants were inserted under general anaesthesia supported via the Biomet 3i Encode Complete System. Due to the fact, the prosthetic reconstruction was implemented only months ago, there a no long-term follow ups until today. Thitherto the patient seems to be happy with her new prosthesis. This case report shall be an indication enhancement for implant-supported prosthetics in risk factor patients.

Schlagwörter: Implantate, Biomet 3i Encode, Risikopatienten, Risikofaktore

Konferenz/Veranstaltung:
3.-4. Dezember 2010
1st Biomet 3i Symposium
Wien

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 525,  Sprache: Deutsch
Klinische und histologische Verlaufsbeobachtungen der Hart- und Weichgewebsrespons nach Augmentationen unter Verwendung von OsseoGuard® Kollagen Membranen
Meier, Jens

This prospective study summarizes the clinical outcome in 60 cases of augmentative procedures with special regard towards amount of swelling, pain and possible inflammatory effects or complicationsas well as handling and histological features in 2-stage procedures when possible. The low expression of resorbtive cell reactions and de novo bone formation up to the former membrane level show the excellent tissue integration. There were no membrane associated complications. The stability of the bone substitute war perserved intil intergration was complete even in difficult cases. In those 5 cases with dehiscences and partial or complete loss of augmentation material the cause was either the dimension of the defekt or the muscular activity in the augmented area.

Schlagwörter: Augmentationen, Sinusbodenelevation, bone substitutes, Knochenaufbaumaterial, Implantate

Konferenz/Veranstaltung:
Dec. 3-4, 2010
1st Biomet 3i Symposium
Vienna, Austria

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 507,  Sprache: Englisch
Plasma Bleaching 'Having a Whiter Future'
Sood, Ravi/B, Shashit Shetty/Hans, Manoj/Nayak B., Gurudutt

Tooth bleaching has become a popular aesthetic service in dentistry. Hydrogen peroxide is a widely used bleaching material that is effective and safe. In office systems use 30%-40% H202 and a high intensity light source. Application of light source might enhance bleaching by heating the H202 but has some potential complications.Plasma is the fourth state of matter also known as "Ionized Gas" and has potential biomedical applications because it is non thermal and nontoxic and can be realized in simple hand-held device.
Room temperature plasma can be used for tooth bleaching with much better results and has an edge over the potential complications with the conventional in office techniques. Thus a combination of plasma treatment and H202 gels are being considered as an effective method of tooth bleaching.This poster presents plasma bleaching as the recent bleaching technique with better results on the safer side.

Schlagwörter: bleaching, plasma, hydrogen peroxide, in-office

Poster Award: Best Poster Presentation

Konferenz/Veranstaltung:
May 27th-29th, 2010.
XI FODI & IES Post Graduate Convention
Bangalore

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 511,  Sprache: Englisch
Effect of Er:YAG laser beam angle and focal distance on the ultrastructural morphology of enamel
Irani, Rukshin S./Thukral, Naresh/Sathe, Sucheta/Hegde, Vivek

Aim & Objective: To evaluate the ultra structural morphology of enamel irradiated with different parameters of the Er: YAG laser & its effect on clinical procedures involving enamel.
Materials & Method: Thirty-five non-carious human premolars that were extracted for orthodontic purposes were selected &randomly divided into 7 groups. The teeth of group 1-3 were evaluated for different focal distances & the teeth of group 4-7 were evaluated for variable beam angles. When evaluating variable focal distances of 5mm, 7mm, & 10mm the beam angle was kept constant at 90° for group 1-3. When evaluating different beam angles of 30, 45, 60 & 90°, the focal distance was kept constant at 7mm for group 4-7. The laser irradiation was performed in a noncontact mode in all teeth. The teeth of each group were treated for 10 sec. The parameters that were kept constant for all groups were pulse energy of 250mJ with 15Hz frequency at very short pulse (VSP).
After irradiation enamel surfaces were analyzed under ESEM.

Schlagwörter: beam angle, focal distance, Er:YAG laser, apparatus, ESEM

Poster Award: Best poster (Research category)

Konferenz/Veranstaltung:
21st-23rd November 2008
23rd FODI & 16th IES National Conference
Chandigarh, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 512,  Sprache: Englisch
Lightening whitening for your dazzling pearls
Shakya, Vijay Kumar/Chandra, Anil

Many individuals desire a "bright" smile and white teeth, and consider dull and stained teeth cosmetically unattractive. Unfortunately, without preventive or remedial measures, stained teeth are almost inevitable due to the absorbent nature of dental material. Everyday activities such as smoking or other oral use of tobacco products, and eating, chewing, or drinking certain foods and beverages (in particular coffee, tea, and red wine) cause undesirable staining of surfaces of teeth.
Dental gel compositions containing active oxygen liberating ingredients have been disclosed in the prior art for whitening teeth. Such gel compositions although effective for whitening teeth require multiple applications of the gel over a period of one to two weeks to provide the desired whitening effect.
There is a continuing need for a rapid tooth whitening system, which can be safely applied by the wearer with or by a specially trained dental personnel. The poster compares different available options regarding instant tooth whitening.

Schlagwörter: white teeth, whitening gel, tooth whitening system

Poster Award: awarded as best poster

Konferenz/Veranstaltung:
16-18 May 2008
9th National FODI & IES Post Graduate students convention
Goa, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 502,  Sprache: Englisch
Nobel-Active in severe case of periodontal disease
Nilius, Manfred/Nilius, Mirela-Oana/Nikolic, Simone/Nikolic, Robert/Arentz, Jochen

A multiplicity of therapeutic possibilities is available in modern implantology. For using implants in severe periodontal cases a two step procedure is recommended. Immediate loading of implants after extracion was rejected predominantly. In the past 3D-planning and guided templates were indicated for edentulous or semitoothless jaws. For transdental implant planning and guided surgery a new approach is presented. Transdental Guided Implant Planning and Positioning (TdGIP) permits an immedate implantation post extractionem and immedate funcional loading with crown and/or bridges. The procedure was flanked by antimicrobiotial photodynamic therapy and YSGG laser treatment.

Schlagwörter: NobelActive, NobelGuide, Periodontal disease, Transdental Guided-Implant-Planning (TdGIP)Implants, 3D-planning, Navigation, templates, immediate loading, photodynamic therapy, Periobridge, YSGG-Waterlase

Poster Award: 2nd place in the Patient Presentation Poster, Senior Clinican, Nobel-Active in severe case of periodontal disease

Konferenz/Veranstaltung:
September 11th-13th, 2008
Nobel Biocare World Tour 2008
Maastricht

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 503,  Sprache: Englisch
Improving interactive learning in dental education
Sagheb, Keyvan/Schulz, Peter/Bemsch, Andreas/Al-Nawas, Bilal

Mayor efforts focused during recent years on the improvement of dental education. In continuation of these endeavours we have developed an interactive E-learning-programme (ILKUM) based on the standards required by ADEE (Association for Dental Education in Europe). Presentation of ILKUM to students revealed their overwhelming interest, boosting our concept of "blended learning". The current results encourage further investments in interactive learning, concentrating on the utilization of mobile media such as iPads as well as iPhones.

Schlagwörter: ILKUM ( Interactive E-learning-database), ADEE (Association of Dental Education in Europe), Blended Learning,iPad, e-learning

Poster Award: Bernd-Spiessl-Award: best Student Poster

Konferenz/Veranstaltung:
June 17th-19th, 2010
6th International Bernd-Spiessl-Symposium for Innovative and Visionary Technologies in Cranio-Maxillofacial Surgery
Basel, Switzerland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 486,  Sprache: Englisch
Nondestructive Visualization of Demineralization using µCT-Synchrotron Radiation
Lautensack, Julia/Gräber, Hans-Georg

The application of synchrotron radiation for non-destructive study of human enamel during in situ demineralisation was investigated. Enamel samples of freshly extracted caries free third molars were prepared. One sample (control) was directly examined using synchrotron micro computed tomography.
The other samples were integrated into four removable intraoral mandibular appliances under gold-micromeshes. Each appliance was worn by a randomly chosen participant throughout day and night. The desired demineralisation was therefore generated in a natural way in the oral cavity by acid producing bacteria and consume of acid and carbohydrate containing food. The depth and grade of structural changes were quantified after either 21 or 29 days of exposition in the oral cavity.
By using µCT-synchrotron radiation we were able to visualise and quantify initial and further progressed stages of demineralisation. The development of mineral loss was dependent on the exposing time of the samples in the oral cavity and the individual nutrition behaviour and salivary properties of the participants.

Schlagwörter: synchrotron radiation, enamel, demineralization, in situ

Poster Award: 1.Preis

Konferenz/Veranstaltung:
November 24th, 2007
Zahnärztetag, Verleihung des 21. DGZMK BZÄK DENTSPLY Förderpreises
Düsseldorf, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 489,  Sprache: Deutsch
Der Einfluss von SNPs im CD14- und TLR4-Gen auf die subgingivale Besiedlung mit Pardontopathogenen
Schulz, Susanne/Klapproth, Jana/Zimmermann, Uta/Reichert, Yvonne/Stein, Jamal M./Gläser, Christiane/Schaller, Hans-Günter/Reichert, Stefan

Background: Periodontitis is characterized as a chronic inflammatory disease. Periodontopathogens induce innate responses amongst others via CD14 and 4 resulting in activation of NF-κB. Functional important SNPs are described for these genes. The aim of this study was to evaluate links between SNP and the subgingival occurrence of periodontopathogens.
Patients and Methods: 133 periodontitis patients (chronic periodontitis: n=60, mean age: 48.7+9.7y, aggressive periodontitis: n=73, mean age: 41+9.9y) and 80 healthy controls without periodontitis were included in the study. SNPs in CD14 (c.-159C>T), in TLR4 (Asp299Gly, Thr399Ile) were determined by RFLP. Subgingival bacterial colonization (A. actinomycetemcomitans, P. gingivalis, P. intermedia, T. forsythia, T. denticola) was analysed molecularbiologically using the micro-Ident®test.
Results: Associations between genotype and the occurrence of periodontopathogens could be shown: P. intermedia occurred less frequently in individuals positive for the TT genotype of CD14-SNP c.-159C>T (OR=0.36, 95%CI: 0.14-0.91, p=0.045). In binary logistic regression analyses, the associations for TT-genoytpe (OR=0.31, CI: 0.12-0.81, p=0.017) could be proven considering age, gender, smoking, and clinical attachment loss as confounding factors. No genotype dependent association with subgingival occurrence of periodontopathogens could be proven for SNPs in TLR4. However, no significant association with chronic and or aggressive periodontitis and polymorphisms in CD14 and TLR4 could be proven.
Conclusions: Although, the CD14 c.-159C>T polymorphism could be shown to be associated with subgingival colonization with P. intermedia there is no evidence that CD14 and TLR4 polymorphisms investigated are independent risk factors for chronic or aggressive periodontitis in German periodontitis patients.

Schlagwörter: Parodontitis, SNP, CD14, TLR4, Pardontopathogene

Poster Award: 2. Posterpreis der Deutschen Gesellschaft für Parodontologie

Konferenz/Veranstaltung:
05.-07.11.2009
Deutscher Zahnärztetag 2009
München, Deutschland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 492,  Sprache: Deutsch
Kostenaufwand der unterstützenden Parodontitistherapie
Pretzl, Bernadette/Eickholz, Peter/Kaltschmitt, Jens/Wiedemann, Denise

Objectives: Assessment of effort (number of visits) and costs of tooth preservation 10 years after initiation of anti-infective therapy.
Methods: Data of 98 patients who had received active periodontal treatment 10 years ago by the same examiner were analyzed to gather information on effort and costs of supportive periodontal therapy (SPT). Clinical examination, interleukin-1 polymorphism test (IL-1), smoking, search of patients' files (i.e. initial diagnosis), as well as a questionnaire on medical history and socioeconomic data were performed. Statistical analysis was performed using multivariate linear regression analysis.
Results: During 10 years of SPT patients had 14.8 ± 7.4 visits. Number of visits was statistically significantly higher for individuals with a mean PCR >= 24%. The number of subgingival scalings per tooth ranged from 0 to 14 (mean: 1.2 2.1). On tooth level several confounders could be identified: tooth type, initial bone loss, furcation involvement, abutment status, and previous regenerative surgery (p <= 0.003). Costs for therapy per tooth during SPT ranged from 1.21€ to 266.26€ with a mean value of 60.73€ ± 42.05€. On tooth level the tooth type, initial bone loss, abutment status, furcation involvement, and previous regenerative surgery showed statistical significance (p <= 0.002).
Conclusion: Costs for tooth retention via SPT are relatively low compared to alternatives (i.e. implants or fixed bridgework) even in periodontally impaired teeth.

Schlagwörter: UPT, Kosten, Zahnerhalt

Poster Award: 1. Posterpreis 2008

Konferenz/Veranstaltung:
15. November 2008
NAgP-Jahrestagung
Bundeswehr-Zentralkrankenhaus Koblenz

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 477,  Sprache: Englisch
Mechanical Properties of Heat-curing Resins by Stress-Strain Diagrams
Bortun, Cristina Maria/Faur, Nicolae/Cernescu, Anghel/Porojan, Sorin/Sandu, Liliana

Objectives: General objectives were based on multidisciplinary research of biomaterials used in dental medicine and are focused on the mechanical properties of dental prostheses.
Materials and Method: We evaluated the mechanical properties of heat-cure resins, such as Meliodent (Heraeus Kulzer, Senden, Germany) and Royaldent Plus (Palatinal Foggyarto Kft., Budapest, Hungary). In accordance with complete-denture technology, we made samples from these materials, which were tested with Zwick Roell equipment (testXpert software).
Results: There were noticeable differences, depending on material type. Based on tensile tests, we determined stress-strain diagrams for the comparative evaluation of Royaldent and Meliodent mechanical properties: (for Royaldent) ultimate tensile strength, 71.5 MPa; yield strength, 4.24 MPa; total elongation, 8.46 %; Young\'s modulus, 1019.25 MPa; (for Meliodent) ultimate tensile strength, 63.29 MPa; yield strength, 4.22 MPa; total elongation, 7.9 %; Young\'s modulus, 1215 MPa. Based on data tests and processed statistics and diagrams, stress-strain was determined by a theoretical characteristic curve of linear variation according to the equation: (σ - Tensile Stress [MPa]; ε - Strain [%]). To determine a and b parameters, we used the program Table CurveTM 2D, where stress and specific deformation registered values were defined, based on defined data from which we selected, as a theoretical characteristic curve, the diagram that best described the represented points set.
Conclusions: The methods allowed for the evaluation of the tensile strength of dental prostheses, and the certification of dental materials\' quality. The registered results showed the brittle characteristics leading to material breaking, illustrated by stress-strain shape diagrams and samples breaking without registering massive plastic deformation.

Schlagwörter: heat curing resins, mechanical properties, stress/strain diagrams

Konferenz/Veranstaltung:
April 1st-4th, 2009
IADR 87th General Session
Miami, Florida, USA

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 468,  Sprache: Deutsch
Vergleich der periimplantären Situation zwischen Steg- und Kugelkopf-retinierten Totalprothesen
Lachmann, Stefan/Kimmerle-Müller, Evi/Gehring, Kristina/Axmann, Detlef/Higuchi, Daisuke/Haas, Robert/Weber, Heiner

Aim: Aim of the investigation was a comparison of the clinical, microbiological and immunological situation of the peri-implant tissues in edentulous patients wearing long-standing lower complete dentures retained by either Dolder bar or ball attachments.
Methods: During a regular recall visit (mean time since implant insertion: 7 years) the following findings were examined in 10 individuals with good oral hygiene, matched for age and gender (mean age 71 years) and wearing either a Dolder bar or ball retained complete mandibular denture: sulcular fluid flow rate (with Periotron device), plaque- and bleeding scores, pocket probing depth, implant stability (Periotest device), subgingival bacterial plaque samples (PCR diagnostics, Hain MicroIdent), and sulcular concentrations of the mediators interleukin 1 beta and prostaglandin E2 (total concentration per site and per µl sulcular fluid in 120 seconds).
Results: No statistically significant differences could be observed between the two groups of patients with Dolder bar and ball retained implant restorations with regard to their peri-implant clinical, microbiological, and immunological findings.
Conclusions: Having in mind the relatively small number of patients included in the investigation the microbiological and immunological findings confirm the nearly identical pattern of influence , for either retentive concept, on the peri-implant soft tissue observed clinically even after a long period of function.

Schlagwörter: Implant supported complete denture, Dolder bar, ball attachment, microbiology, sulcular fluid, interleukin 1 beta, prostaglandin E2

Poster Award: Bestes Poster eines Nichthabiliterten

Konferenz/Veranstaltung:
3.-5. Mai 2007
56. Jahrestagung der DGZPW
Bonn

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 470,  Sprache: Englisch
SEM study on dentin/resin interface in primary teeth
Yoonis, Emaan/Matoušek, Aleš/Kukletová, Martina

Dentinal adhesives Excite, Single bond, Prime bond, Prompt-L-pop Adper, Xeno III and AdheSe were applicated into class I cavities preparated into extracted primary teeth and they were restored with EvoCeram. The teeth were prepared for investigation under scanning electron microscope using Epovac and Struers Tegra polishing system. There was no substantial difference in morphology of the dentine/resin interface between the techniques studied. This fact may be of importance in the restoration of primary teeth because the number of steps and the procedure duration can be significantly reduced.

Schlagwörter: Primary dentition, dentine adhesives, hybride layer, SEM, esthetic filling, self-etching technique, total-etch technique

Poster Award: AEEDC Dubai 2009 Poster Award, 2nd Price

Konferenz/Veranstaltung:
March 10-12th, 2009
UAE International Dental Conference & Arab Dental Exhibition AEEDC
Dubai

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 458,  Sprache: Deutsch
IL-1 Polymorphismen und Häufigkeit parodontale Leitkeime bei Patienten mit akutem Myokardinfarkt (AMI)
Stein, Jamal M./Conrads, Georg/Chrobot, Jaroslaw/Scheidt, Wolfgang von/Lampert, Friedrich/Kuch, Bernhard/Said-Yekta, Sareh

Background: Numerous studies point to an association between periodontal and cardiovascular diseases. The results, however, are not consistent. Genetic factors of host response and the influence of periodontal pathogens have not sufficiently been investigated although they might be responsable for the mentioned discepancies. The aim of this study was to examine the prevalence of periodontal pathogens and polymorphisms in the interleukin-1 (IL-1) gene cluster in patients after acute myocardial infarction (AMI).
Material and Methods: In 54 patients with AMI (35-50 years) and 50 healthy probands (36-61 years) the following parameter were recorded: periodontal probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), plaque index (PI) and gingival index (GI). In all patients and controls subgingival plaque samples were analysed for periodontal pathogens Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf) and Prevotella intermedia (Pi) using dot blot hybridisation. Further, in 39 AMI patients and 50 controls allele frequencies of IL-1A, IL-1B and IL-1RN were examined using PCR with reverse hybridisation.
Results: In patients with AMI all periodontal parameters (PD, CAL, BOP, PI, GI) were significantly higher than in healthy controls. Among different cut-off levels, the frequency of more than 50% sites with PD >= 4 mm showed the highest discrepancy between both groups (33% vs. 0%, p50% PD >= 4 mm) versus without (= 4 mm) generalized periodontitis had two different IL-1-haplotype patterns.
Conclusions: The results confirm the association between AMI and periodontitis. A.a. and P.g. might be risk indicators for AMI. Two different IL-1 haplotypes may explain previous discrepancies in the association between cardiovascular diseases and periodontitis.

Schlagwörter: periodontitis, myocardial infarction, interleukin-1

Konferenz/Veranstaltung:
26.-27. September 2008
Jahrestagung der Deutschen Gesellschaft für Parodontologie
Nürnberg, Deutschland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 448,  Sprache: Englisch
About the importance of odontological documentation of ante-mortem details of two soldiers killed in World War II
A contribution of the German Academy of Forensic Odontostomatology
Kirsch, Hans-Peter

The identification of skeletons by dental means is based on the maceration of the jaws, photography, X-rays, X-ray examination and comparison with AM documents. The case of two German soldiers, killed in World War II and found after more than 60 years, shows the importance of recording odontological details of the armed forces servicemen. Age estimation by different methods, e.g. by the methods of KVAAL and BANG/RAMM, not always lead to accurate results.

Schlagwörter: forensic odontology, age estimation, documentation, identification

Konferenz/Veranstaltung:
25.-26. September 2008
The Annual A.F.I.O. Meeting on Forensic Odontology - XVIII ème Congrès A.F.I.O.
Nantes, France

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 438,  Sprache: Englisch
Mucormycosis - A case report
Ramdas, Naik Shantala/Lingappa, Ashok

Mucormycosis is an oppurtunistic fungal infection more commonly seen in immunocompromised individuals. Herewith presenting a similar case involving the maxillary sinus in a middle aged male with uncontrolled diabetes.

Schlagwörter: mucormycosis

Poster Award: Best poster in infection category

Konferenz/Veranstaltung:
4th and 5th July 2007
Tripple O National symposium
Belgaum, Karnataka, India

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 425,  Sprache: Englisch
C-6-S Levels in PMICF under Orthodontic Forces
Intachai, Imjai/Jotikasthira, Dhirawat/Suzuki, Boonsiva/Suzuki, Eduardo Yugo/Krisanaprakornkit, Suttichai/Kongtawelert, Prachya

Objective: To detect chodroitin-6-sulfate (C-6-S) in peri-miniscrew implant crevicular fluid (PMICF) under orthodontic forces.
Materials and Methods: Two experiments were carried out. The first experiment period was five weeks. Five male patients, aged 22.0 ± 2.9 years and with four premolars extracted, comprised the first experiment. Ten miniscrew implants were placed buccally, bilaterally, in the alveolar bone between the roots of maxillary posterior teeth. Sentalloy closed-coil springs (50 g) were used to load the miniscrew implant and to move the maxillary canines distally. During the unloaded period, PMICF samples were collected on days 1, 3, 5 and 7 after miniscrew implant placement; and on days 14, 21, 28 and 35 during the loaded period. The second experiment period was ten weeks. Three female and two male patients, aged 20.0 ± 1.9 years and with four premolars extracted, comprised the second experiment. Ten miniscrew implants were used as anchorage. During the loaded period, the PMICF samples were collected on days 14, 21, 28, 35, 42, 49, 56, 63, and 70. Clinical mobility assessments of the miniscrew implants were recorded at every visit. The competitive ELISA with WF6 monoclonal antibody was used to detect C-6-S levels in the PMICF samples.
Results: In the first experiment, the C-6-S levels during the unloaded period ranged from 0.00 to 58.53 ng/ml, and those during the loaded period ranged from 0.00 to 679.89 ng/ml. Median values of C-6-S levels during the loaded period were significantly higher than those during the unloaded period (P = 0.008). In the second experiment, the C-6-S levels during the unloaded period ranged from 0.00 to 758.03 ng/ml, and those during the loaded period ranged from 0.00 to 6,348.90 ng/ml. Median values of C-6-S levels between the unloaded and loaded periods were not significantly different. We noticed that one miniscrew implant failed at day 70. Interestingly, the C-6-S level in PMICF around that particular miniscrew implant was dramatically elevated 14 days earlier.
Conclusions: The C-6-S levels could be precisely detected in PMICF. To draw a reasonable conclusion for using the C-6-S level as a biomarker for assessing alveolar bone remodeling around miniscrew implants, further investigation with an increased sample size is needed.

Schlagwörter: miniscrew implants, peri-miniscrew implant crevicular fluid, chondroitin-6-sulfate

Poster Award: The second place of the outstanding presentations

Konferenz/Veranstaltung:
December 14-16, 2007
The 6th Asian Implant Orthodontic Conference (AIOC) & TAO Annual Conference
Nan Shan Educational & Training Center, Taichung, Taiwan

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 428,  Sprache: Deutsch
Patientenbezogene Langzeitergebnisse 10 Jahre nach parodontaler Therapie
Pretzl, Bernadette/Kaltschmitt, Jens/Berbig, Janet/Eickholz, Peter

Objectives: Assessment of patient-related factors contributing 1) to tooth loss and 2) to the quality of treatment outcome 10 years after initiation of anti-infective therapy.
Methods: All patients who had received active periodontal treatment 10 years ago by the same examiner were recruited consecutively until a total of 100 patients was re-examined. Re-examination was performed by a second examiner and included: clinical examination, test for interleukin-1 polymorphism (IL-1), smoking history, review of patients' files (i.e. regularity of supportive periodontal therapy: SPT). Statistical analysis included Poisson and logistic regressions.
Results: Fifty-three patients attended SPT regularly, 59 were females, 38 were IL-1 positive. Poisson regressions identified mean plaque index during SPT, irregular attendance of SPT, gender (p = 0.0001), initial diagnosis (p = 0.0005), IL-1 polymorphism (p = 0.0007), smoking (p = 0.0053), and age (p = 0.0487) as factors significantly contributing to tooth loss. Additionally mean plaque index during SPT (p = 0.011) and irregular SPT (p = 0.002) were associated with a worse periodontal status 10 years after initiation of therapy.
Conclusion: The following risk factors for tooth loss were identified: ineffective oral hygiene, irregular SPT, IL-1 polymorphism, initial diagnosis, smoking, age, and gender.

Schlagwörter: long-term results, periodontal therapy, prognosis

Poster Award: 1. Posterpreis 2007

Konferenz/Veranstaltung:
17. November 2007
NAgP-Jahrestagung
Leipzig

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 431,  Sprache: Englisch
Biomecanical evaluation of miniscrew implants in vitro
Suzuki, Boonsiva/Suzuki, Eduardo Yugo/Doungsaard, Kanchana/Prasoothavee, Prakarn/Thong-ngarm, Weeranuch/Chuensombat, Sorapong/Janhom, Apirum

Background: Bone quality plays an important role in the success of orthodontic miniscrew implants. The mechanical properties of bone are highly related to the mineral content, which varies widely according to function and histology. However, in vitro methods for evaluating biomechanical properties of miniscrew implants have not been reported.
Purpose: The aim of this study was to assess the biomechanical performance of miniscrew implants using bone samples which were demineralized by timed chemical immersion to alter the mineral content.
Materials and Methods: Sections of fresh rib bones from adult pigs were selectively demineralized by timed immersion in 1 % ethylenediamine-tetraacetic (EDTA). Specimens were removed from the solution after 0 (control), 6, 10, 16, 30 and 50 days and embedded in acrylic blocks. Quantification of bone density was performed using radiographic images processed with Photoshop software. Fifty miniscrew implants (8 mm long and 1.6 mm in diameter, BKM, Korea) were inserted. Maximum insertion torque was recorded with a toque gauge. Pullout strength was tested using an Instron Universal testing machine. Statistical analysis was performed using Kruskal-Wallis Test and Spearman correlation coefficients.
Results: There was a systematic decrease in bone density that was followed by a significant decrease in the biomechanical properties of the miniscrews. High correlation (r = 0.91) was observed between maximum insertion torque and maximum pullout strength.
Conclusions: The biomechanical properties of miniscrew implants can be evaluated in vitro using bones obtained from a single species prepared with the selectively demineralized bone technique. The proposed method can be used to facilitate comparison between different miniscrew implant systems, avoiding the inaccuracy observed in conventional methods.

Schlagwörter: miniscrew implants, orthodontics, biomechanics, in vitro

Poster Award: Outstanding Poster Award - 1st place

Konferenz/Veranstaltung:
December 14th-16th, 2007
The 6th Asian Implant Orthodontic Conference (AIOC)
Taichung, Taiwan

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 418,  Sprache: Deutsch
Klinische Untersuchung zur medikamenteninduzierten vs. strahlentechnischen Speicheldrüsenschonung
Hey, Jeremias/Gerlach, Reinhard/Kuhnt, Thomas/Gernhardt, Christian Ralf

After radiation treatment of head and neck cancer quality of life and pathological changes in oral health are significantly dependent on functional insufficiency of salivary glands. Satisfactory therapies for treating resulting diseases such as xerostomia, radiation caused dental decay and osteoradionecrosis have not yet been found.
New strategies aim at containing these side effects without reducing radiation dose. We test protectionary effects of 3dimensional conformal radiation therapy (3D-CRT) including medicamentary treatment using radioprotector and contralateral parotid gland sparing.
Using a sample of 106 patients under radiation treatment of head and neck cancer we measured changes of pH-value, salivary flow rates and buffer capacity to analyse the protectionary effects of Amifostin in contrast to contralateral parotid gland sparing. A cumulative dose of between 64Gy - 70Gy was given to primary planning target volume.
Exact measurement of the radiation dose was achieved by using CT-based dose-volume-histograms. We extracted salivary before, during and after radiation treatment as well as one six and twelve month after radiation. Based on salivary flow rates we tested the protection of salivary glands/normal tissue compliance probability of Parotiden by Amifostin and contalateral parotid gland sparing controlling for the amount of radiation given.
The best protection in these experiments was found with contralateral parotid gland sparing by using modern 3D-CRT. Although Amifostin offers some protection, too, it is less effective and due to high costs and considerable side effects not suitable for routine treatments.
The study was supported by a research grant of Deutsche Krebshilfe.

Schlagwörter: Radiotherapie, Speicheldrüsenschonung, Amifostin, Speichel

Poster Award: 2. Platz Dentsply Förderpreis

Konferenz/Veranstaltung:
21.11.-24.11.2007
Deutschr Zahnärztetag
Düsseldorf

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 381,  Sprache: Deutsch
Retrospektive Longitudinalstudie über die langfristige klinische Bewährung Teleskopprothesen unter besonderer Berücksichtigung der Instandhaltungskosten
Rehmann, Peter/Weber, Andrea/Balkenhol, Markus/Wöstmann, Bernd/Ferger, Paul

The aim of this retrospective longitudinal study was to assess the survival rates and the follow-up costs of telescopic crown retained dentures.The study was based on the data of 554 telescopic crown retained dentures and their 1758 abutment teeth. All prostheses were delivered in the Department of Dental Prosthetics of the Justus-Liebig-University of Giessen between 1995 and 2004.The 90%- (50%-) survival rate of the prostheses was determined at 6,4 years (9,3 years).The 90%- survival time of the abutment teeth was determined after 6,9 years.Because of the high incidence of following treatments in the first year after insertion of the prosthesis the highest follow-up costs of approximately 100 € were noted in this period. Then the costs dropped to averagely 55 € a year.Overall the repairs of facings of the secondary telescopic crowns caused the highest costs during the functional period of the prosthesis. More than one third of the whole follow-up costs were caused of the renewal of facings.

Schlagwörter: Longitudinaluntersuchung; Teleskop; Überlebensrate; Zahnersatz, festsitzend/herausnehmbarer

Poster Award: Bestes Poster eines Nichthabilitierten

Konferenz/Veranstaltung:
27.04.-30.04.2006
55. Jahrestagung der Deutschen Gesellschaft für zahnärztliche Prothetik und Werkstoffkunde (DGZPW)
Basel (Schweiz)

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 382,  Sprache: Englisch
Prosthetic rehabilitation of a patient with scleroderma- induced microstomia: a clinical report
Jivanescu, Anca/Bratu, Dorin/Negrutiu, Meda

The clinical and technical steps involved in the fabrication of the flexiblecomplete denture specifically indicated because of the advanced stage ofmicrostomia associated with systemic scleroderma are reported.

Schlagwörter: microstomia, scleroderma, flexible complete denture

Konferenz/Veranstaltung:
12-14 April
12 th Congress of the Bass
Istanbul, Turkiye

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 359,  Sprache: Englisch
The 'Implant Guided Palatinal Distractor (IGPD)'
Nilius, Manfred/Nilius, Mirela-Oana/Goeken, Rainhard/Eggharter, Iurii/Zahn, Torsten/Haugwitz, Georg/Bouhjar, Nabil Ben

Surgery of craniofacial deformities is a complex task that requires careful preoperative planning. In this field Nobel-Guide-System made a great impact of predictable implantology. Using these for computer-aided surgery (CAS) the patient outcome of extreme dental and facial makeovers can be anticipated. The following case report shows new indications for dental implants by using Nobel-Guide- System for fixation of a prefabricated "Implant Guided Palatinal Distractor" (IGPD) and for an implant bridge. Thus - embedding dental implantation in maxillofacial procedures like LeFort-Osteotomy,forced guided palatinal distraction, chin augmentation and septorhinoplasty can be performed in a single-step operation. Operation time and costs can be reduced.

Schlagwörter: Esthetic facial surgery, Nobel-Guide, facial implants, palatinal distraction, dental implants

Poster Award: Senior Poster Award

Konferenz/Veranstaltung:
19th.-21st. Oct. 2006
Nobel Biocare World-Tour, Dresden, Germany
Dresden

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 360,  Sprache: Englisch
Tri-axial Accelerometric Analysis of Dynamic Patterns of Mandibular Movements
Pelivan, Ivica/Valentic-Peruzovic, Melita/Michieli, Ivan/Dubravic, Amir/Catic, Amir/Alajbeg, Iva/Illes, Davor

The dynamics of mandibular movements is determined by neuromuscular physiology as well as pathophysiology of all parts of the masticatory system. The objective of this pilot study was to examine if dynamic features of mandibular movements in healthy subject can be described and extracted through mandible acceleration measurements.

Schlagwörter: mandibular biomechanic, temporomandibular joint, accelerometry

Poster Award: IADR CED Travel Stipend Award

Konferenz/Veranstaltung:
September 13-16, 2006
PEF 2006 - Pan European Federation of IADR
Trinity College Dublin, Ireland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 362,  Sprache: Deutsch
Retrospektive Longitudinalstudie über die Bewährung von Freiendteleskopen mit ausschließlicher Verankerung auf den Unterkiefereckzähnen
Rehmann, Peter/Schmitt-Plank, Cathrin/Balkenhol, Markus/Wöstmann, Bernd/Ferger, Paul

The aim of this retrospective longitudinal study was, to assess the clinical long term performance of telescopic crown retained dentures with abutment teeth, exclusively located in the canine region of the lower jaw. In addition, the factors - influencing the survival time of the abutment teeth - as well as the nature and the number of the follow-up treatment measures were determined.The evaluation based on records of 84 patients who had been treated in the Department of Prosthetic Dentistry, Justus-Liebig-University Giessen, Germany.The 90%- (50%-) survival probability of the dentures was not achieved after 4.0 years (9.1 years). Furthermore, the 90%- (50%-) survival probability of the abutment teeth, determined at 4.0 years (12.9 years), was comparable to other studies. It was revealed, that the vital abutment teeth had a significant higher survival rate and survival time in comparison to abutment teeth, treated endodontically and provided with root canal posts.The patients' assessment of the telescopic crown retained denture was down the line positive (70% were very satisfied, 28% were relatively satisfied, 2% were dissatisfied).

Schlagwörter: Longitudinaluntersuchung, Teleskop, Überlebensrate, Zahnersatz festsitzend/herausnehmbarer

Poster Award: Bestes Poster eines Nichthabilitierten

Konferenz/Veranstaltung:
14.05.2004
53. Jahrestagung der Deutschen Gesellschaft für Zahnärztliche Prothetik und Werkstoffkunde e.V.
Kiel

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 364,  Sprache: Englisch
Aesthetic and functional Rehabilitation of the face using dental and facial implants
Nilius, Manfred/Anastase, Jana/Goeken, Rainhard/Zahn, Torsten/Nilius, Mirela-Oana/Gherbali, Iurii

A 12-year old female orphan from Romania was transferred into our hospital. The lower jaw showed an enormous tumor in the symphysis mandibulae; diagnosed as an intraosseous venous malformation of the mandible. After resection of the tumor the defect was primarily reconstructed using a microvascularized fibula-graft. For total makeover of the mouth a computerized tomography was used for positioning the implants. The prosthesis was designed by using a Procera®-Implant Bridge. Because of vertical and horizontal loss of the anterior arch, a customized chin implant was prefabricated to improve the esthetical facial symmetry.Using dental and facial implants together in one operation is an option for full-face makeover. It reduces operating time and cost, avoids a second bone grafting procedure, improves the esthetic outcome and thus is beneficial for the patient and the dentist.

Schlagwörter: facial implants, computer assisted implantology, Simplant, facial reconstruction, immedate function, implant-bridge

Poster Award: Poster Award Fallpräsentation, 2. Preis

Konferenz/Veranstaltung:
09th - 11th March 2006
Nobel Biocare World-Tour Frankfurt,
Sheraton-Hotel and Towers

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 329,  Sprache: Englisch
Validation of interdependency between inner structure visualization and structural mechanics simulation
Kober, Cornelia/Erdmann, Bodo/Hellmich, Christian/Sader, Robert/Zeilhofer, Hans-Florian

The interdependence of inner architecture of bone and its functional loading is one of the fundamental principles of Biomechanics. Our objective is to demonstrate this interdependence for the case of a human mandible by qualitative correspondences of a 3D-profile representing the organ's inner structure and simulated volumetric strain.
We simulated a lateral bite on the leftmost premolar of a partially edentulous human mandible characterized by beginning atrophy of the alveolar ridge. By means of visualization techniques developed by the group, a volumetric profile of bone mineral density based on CT numbers could be given. We compared regions of elevated volumetric strain with regions of elevated tissue density and vice versa. Notably, dominant compression besides the biting tooth corresponds to the atrophied region there.

Schlagwörter: human mandible, finite element simulation, biomechanics, inner architecture of bone, inner structure visualization

Poster Award: CARS 2005 Poster Award, 2nd Prize

Konferenz/Veranstaltung:
June 22 - 25, 2005
CARS 2005 Computer Assisted Radiology and Surgery
Berlin, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 299,  Sprache: Deutsch
Die Serum-CRP-Konzentration vor und nach Parodontitis-Therapie
Zahn, Bernhard/Schacher, Beate/Oremek, Gerhard/Sauer-Eppel, Hildegund/Ratka-Krüger, Petra

Inflammation caused by periodontitis may have numerous systemic effects. One of the mediators influenced by periodontitis is C-reactive protein (CRP). Aim of this study was to determine if healthy subjects without peridontitis have a lower CRP-concentration compared to patients with chronic periodontitis. Further it should be evaluated if CRP-level decreases after a nonsurgical periodontal therapy. 21 systemically healthy patients with periodontitis (PERIO) and 11 persons without periodontitis as control group (C) were included. All persons had a clinical examination and provided blood to determine the CRP level. Following initial assessment, the periodontitis group received nonsurgical periodontal treatment. 6 weeks later, a second examination and CRP analysis was done. At baseline, subjects with periodontitis had a higher CRP level than the control group (PERIO: 0,36 ±0,3 mg/dl; C: 0,29 ±0,3 mg/dl). Treatment reduced probing depths and bleeding score significantly. After treatment, CRP-level decreased (0,27 ±0,3 mg/dl), but the differences found were not statistically significant. The results of this study point out that patients with chronic periodontitis may have higher CRP-level compared to healthy subjects and that a nonsurgical periodontal treatment can decrease CRP-concentration.

Schlagwörter: C-reaktives Protein, chronische Parodontitis, Entzündung, nichtchirurgische Parodontitis-Therapie

Poster Award: Posterpreis der Deutschen Gesellschaft für Parodontologie

Konferenz/Veranstaltung:
26.-30. Oktober 2005
DGZMK-Gemeinschaftstagung
Berlin

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 301,  Sprache: Englisch
Is the lateral pterygoid muscle palpable?
Stelzenmüller, Wolfgang/Weber, Dominic/Özkan, Volkan/Freesmeyer, Wolfgang B./Umstadt, Horst

The basic requirement for successfully palpating the lateral pterygoid muscle is exact knowledge of muscle topography and the intraoral palpation pathway. After documented palpation of the muscle belly in cadaverous preparations, MRI and EMG also visualized palpation of the lateral pterygoid muscle in vivo. The palpation technique seems to be essential and basically feasible.

Schlagwörter: TMJ, M. pterygoideus lateralis, EMG, MRI, palpation

Poster Award: Best awarded poster presentation

Konferenz/Veranstaltung:
28/11/2004
AFDT
Bad Homburg Maritim Hotel

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 303,  Sprache: Deutsch
Funktionelle Ergebnisse 6 Monate nach intraoraler endoskopisch assistierter Versorgung von dislozierten Kollumfakturen
Schön, Ralf/Gellrich, Nils-Claudius/Schramm, Alexander/Schmelzeisen, Rainer

In dem Zeitraum von Oktober 2000 bis Januar 2002 wurde bei 13 Patienten eine endoskopisch assistierte Versorgung von dislozierten Kollumfrakturen mit Miniplatten durchgeführt.
Material und Methode: Von den 13 Frakturen waren 3 nach medial und 6 nach lateral disloziert. 4 Frakturen zeigten eine axiale Dislokation mit Verkürzung des aufsteigenden Unterkieferastes. 2 Fraktur zeigten ein ausgesprengtes Fragment am Hinterrand des aufsteigenden Unterkieferrandes und bei 8 Patienten waren weitere Unterkieferfrakturen auffällig. Die Frakturversorgung wurde bei allen 13 Patienten über eine intraorale Inzision unter Verwendung von abgewinkelten Bohrern und Schraubendrehern rein transoral durchgeführt. 30° Optiken (Karl Storz, Germany) wurden für die endoskopisch kontrollierte Reposition und Osteosynthese verwendet.
Ergebnis: Unter Verwendung von Endoskopen wurde eine gute Übersicht bei der transoralen Frakturversorgung und Repositionskontrolle insbesondere am dorsalen Rand des aufsteigenden Unterkieferastes erreicht. Postoperative Röntgenbilder zeigten eine regelrechte Reposition. 6 Monate nach Frakturversorgung zeigten die 13 Patienten zufriedenstellende funktionelle Ergebnisse ohne Okklusionsstörungen, mit einer Mundöffnung größer als 40mm ohne Deviation und ohne Limitation bei Laterotrusion.
Schlußfolgerung: Der transorale Zugang mit Gebrauch von abgewinkelten Bohrern und Schraubendrehern bewährte sich als zuverlässige Methode auch bei der Versorgung von dislozierten und mehrfragment Frakturen. Eine Narbenbildung im sichtbaren Bereich und eine Schädigung des N. fazialis wurden bei dem transoralen Zugang vermieden.

Schlagwörter: endoscopic surgery, dislocated condyle fractures, minimal invasive surgery

Poster Award: 2. Posterpreis

Konferenz/Veranstaltung:
Januar 2003
Österreichische Jahrestagung Mund-, Kiefer- und Gesichtschirurgie (ÖGMKG)
Bad Hofgastein, Austria

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 297,  Sprache: Englisch
Clinical Comparison between an Oily Calcium Hydroxide Suspension (Osteoinductal®) and an Enamel Matrix Protein Derivative (Emdogain®) for the Treatment of Intrabony Periodontal Defects in Humans
Stratul, Stefan-Ioan/Rusu, Darian/Benta, Anca/Willershausen, Britta/Sculean, Anton

An oily Calcium Hydroxide suspension (OCHS) has beendocumented clinically and histologically to enhance the bone regeneration inclosed bone defects and to stimulate the periodontal regeneration inintrabony defects. So far, there are no controlled clinical studies tocompare the effect of the OCHS with the effect of other "biological agents"in treating deep intrabony defects. Aim of the study was to compare thetreatment of deep intrabony defects with an OCHS (Osteoinductal®,Osteoinductal GmbH, München, Germany) to an enamel matrix protein derivative(EMD; Emdogain®, Straumann AG, Waldenburg, Switzerland). Thirty healthypatients, each of whom displayed one intrabony defect, were randomly treatedeither with the OCHS (test) or with EMD (control). Soft tissue measurementswere made at baseline and 6 months following the therapy. No differences inany of the investigated parameters were observed were observed at baselinebetween the two groups. No adverse healing response was observed in any ofthe patients. At six months after the therapy, the sites treated with OCHSshowed a reduction in probing pocket depth (PPD) from 8.60 ± 2.06 mm to 3.27± 1.39 mm and a change in clinical attachment level (CAL) from 10.20 ± 2.08mm to 5.80 ± 2.37 mm (p

Schlagwörter: oily calcium hydroxide suspension, enamel matrix proteins, periodontal regeneration

Poster Award: NAgP Posterpreis fur das beste eingereichte Poster

Konferenz/Veranstaltung:
28 October 2004
Hersbsttagung der Neue Arbeitsgruppe Parodontologie NAgP
Mainz, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 277,  Sprache: Englisch
Durability of Bonds between Luting Cements and High-Gold-Content Alloy
Piwowarczyk, Andree/Zatorska, Karina/Lindemann, Klaus/Lauer, Hans-Christoph

Objective: This study determined the long-term bond strength of various luting cements to high-gold-content alloy.Materials and Methods: High-gold-content alloy (Portadur P4; Wieland, Germany) specimens (Ø = 10 mm, h = 1 mm) were fabricated. Bonding substrates were placed into plastic rings and embedded with slow-polymerizing epoxy resin. Material surfaces were ground sequentially to 600-grit using SiC sandpaper. The surface of all specimens were 100 microns Al2O3 abraded at 2.8 bar, 10 s at 10 mm distance. Following luting cements were tested: PermaCem (DMG), RelyX ARC (3M ESPE), Panavia F (Kuraray), Nexus 2 (Kerr), Calibra (Dentsply DeTrey) and RelyX Unicem (3M ESPE). Eight specimens per group were fabricated: Group (A) was aged and tested after 150 day 37°C water storage; Group (B) 150 day at 37°C water storage, then thermocycled (37.500X, 5-55°C). Shear loading tests were performed using a universal testing machine at a constant crosshead speed of 0.5 mm/min. Two-way ANOVA of variance was used to analyze the data (α=0.05).
Results: Significant differences were found between all main effects (all p

Schlagwörter: luting cement, bond durability, artificial aging

Poster Award: Best Poster of Conference

Konferenz/Veranstaltung:
II. Deutsch-Polnisches Stomatologisches Symposium
March 4-5, 2005
Warsaw, Poland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 273,  Sprache: Englisch
Cleaning efficacy of interdental brushes in different interdental space types
Jörß, Daniela/Wolff, Diana/Pioch, Thomas/Dörfer, Christof E.

Introduction: No information is available which factors influence the cleaning efficacy of interdental brushes.
Aim: To evaluate in vitro the cleaning efficacy of interdental brushes in different types of interdental spaces.
Methods: Interdental brushes with diameters of 2, 3, 4 and 5 mm (Curaden AG) were tested in 8 pairs of extracted human molars combined to simulate two types (isosceles and equilateral) of interdental spaces with 4 sizes each. After coating the teeth with a dye to simulate plaque, digital images were taken from the proximal surfaces in a highly standardized setup. The teeth were repositioned and the proximal surfaces were cleaned in a reproducible manner. Post-brushing images were taken as before. After digital subtraction, the cleaned area was measured by pixel count. Percentage of cleaned surface area was taken as cleaning efficacy.
Results: The cleaning efficacy was 10.1± 7.8% (2mm), 16.8± 9.6% (3mm), 23.0± 9.7 % (4mm) and 22.5± 7.8% (5mm) in equilateral interdental spaces. In isosceles the cleaning efficacy was 13.2± 5.1% (2mm), 20.0± 4.7% (3mm), 26.6± 7.7 % (4mm) and 25.9± 7.0% (5mm), respectively. The differences between the different types of interdental spaces were statistically significant (Wilcoxon test for paired samples, p

Schlagwörter: interdental brushes, interdental spaces, cleaning efficacy

Poster Award: ConsEuro-GABA-Poster-Award (3rd place)

Konferenz/Veranstaltung:
05.-07-06.2003
ConsEuro
München, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 252,  Sprache: Deutsch
Langzeitergebnisse 10 Jahre nach parodontaler Therapie. 2. Zahnbezogene Faktoren
Kaltschmitt, Jens/Pretzl, Bernadette/Eickholz, Peter

Objective: Evaluation of tooth-related factors influencing long-term success of systematic periodontal therapy. Main outcome variable for this analysis was tooth loss.
Methods: 38 patients were consecutively recruited. Inclusion criteria were antiinfectious therapy 10 years ago by the same therapist (PE) and a complete set of intraoral radiographs obtained at the initiation of therapy. Clinical examinations, sampling for interleukin-1 polymorphism test, and questionnaire regarding smoking, and oral hygiene, were performed by the same examiner (BP). Tooth loss, type, and location as well as frequency of supportive periodontal therapy (SPT) were recorded from patients' charts. Each tooth was evaluated for bone loss in per cent of root length and type of bone loss (vertical/horizontal) on the radiographs by another examiner (JK).
Results: From a total of 847 teeth 70 teeth were lost in a period of 10 years (8%). Initially 256 teeth exhibited a bone loss up to 20% (tooth loss 4%), 302 up to 40% (5%), 192 up to 60% (11%), 69 up to 80% (19%), and 28 > 80% (36%). Under frequent SPT (21 patients, 479 teeth) tooth loss amounted to 4%, without SPT to 13%. Multilevel regression analysis identified the following factors as preventive against tooth loss: frequent SPT (p = 0.021), little bone loss (p Conclusion: Little initial bone loss, mandibular as well as anterior tooth location, and frequent SPT are positive predictors for tooth retention.

Schlagwörter: Langzeitergebnisse, antiinfektiöse Therapie, unterstützende Parodontitistherapie, parodontaler Knochenabbau, Zahntyp

Poster Award: Posterpreis: 3. Bestpreis 2004

Konferenz/Veranstaltung:
9.-12.9.2004,
DGP-Jahrestagung,
Dresden, Deutschland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 253,  Sprache: Deutsch
Vergleich zweier Entnahmestrategien subgingivaler Plaqueproben für mikrobiologische Gensondentests
Krigar, Diana M./Kaltschmitt, Jens/Radek, Martin/Eickholz, Peter

The aim of this study was to compare the results of a microbiological test from 3 different sites with the results from all three samples pooled in one transport vial.
27 patients suffering from aggressive periodontitis or generalized severe chronic periodontitis participated in this study. Clinical examinations were obtained before (n=10) or after (n=19) antiinfectious periodontal therapy. Microbiological samples were obtained from the three pockets with the deepest probing depths for microbiological analysis. Two sterile paper points were inserted simultanously in the periodontal pockets. One paper point from each pocket was put in a separate transport-vial, the other was pooled (MT3) with the two other paper points of a respective patient in a transport-vial and analysed for Actinobacillus actinomycetemcomitans (AA), Tannerella forsythensis (TF), Porphyromonas gingivalis (PG) and Treponema denticola (TD) with a commercially available RNA-probe test. The logarithmic bacterial load of pooled samples was for all tested bacteria higher than the mean value of the results of the single samples. For TF (p

Schlagwörter: generalisierte schwere chronische Parodontitis, aggressive Parodontitis, subgingivale Plaque, mikrobiologischer Test

Poster Award: Posterpreis: 2. Bestpreis 2004

Konferenz/Veranstaltung:
9.-11.9.2004,
Jubiläumstagung der Deutschen Gesellschaft für Parodontologie (DGP),
Dresden, Deutschland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 254,  Sprache: Englisch
Esthetics in and with All-ceramic Restorations
Bauer, Axel/Zatorska, Karina/Lauer, Hans-Christoph

All-ceramic dental restorations get an impact in prosthodontic therapy concepts due to their esthetic advantage and their excellent biocompatibility - which are the main prerequisites to meet the demands of patients nowadays. However, glass ceramic needs an adhesive cementation to reinforce its weak strength. The limited indication to veeners, inlays, onlays and anterior single crowns caused a long-term success proven by several clinical trials. An "add on" of these indications are now possible by using frames of high tech ceramic zirkonia. The so called "ceramic steel" can be used for three or more unit fixed partial dentures (FPD's) even in the posterior regions. Additionally the high strength and fracture resistance of zirconia provides a thin thickness of crown- and bridge frameworks causing a minimal invasive shape of a tooth preparation. Even ceramic implant abutments and conical taper crowns show an increased survival rate compared to other all ceramic systems.
Unfortunately zirkonia can be only processed by a CAD/CAM based milling machine. To prevent grinding the very strong zirkonia bulk, the pre- or semi-sintered zirkonia, is milled in a 30% enlarged three dimensional form to compensate the shrinkage in the post process of sintering. This procedure saves costs and will offer the replacement of standard porcelain fused to metal restorations by all ceramic single crowns and FPD's in the near future.

Schlagwörter: dental, all-ceramic, CAD/CAM, fixed partial denture, FPD, fused to metal restorations, PFM, esthetic, aesthetic, biocompatible, zirconia, Semi sintered, hot isostatic pressed, embriddlement, flexural strength

Poster Award: Posteraward

Konferenz/Veranstaltung:
2. - 3. April 2004
1. Deutsch-Polnischen Stomatologischen Symposiums der DGZMK
Frankfurt am Main, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 258,  Sprache: Englisch
Chemiluminescence and LED: The Future of Early Oral Cancer Detection?
Saravanan, Ram/Siar, Chong Huat

Advancements in cancer research have led to the innovation of contemporary diagnostic tools for early oral cancer detection. Vizilite® and Glowsticks based on the principle of 'chemiluminescence' and Light Emitting Diodes (LED) are the latest diagnostic tools available for this purpose. Objectives: To evaluate the potential value of chemiluminescence (Vizilite® and Glowsticks) and LED as tools for the early detection of oral cancer, dysplasia and potentially malignant epithelial lesions (PMEL). The efficacy of these tools was assessed in terms of sensitivity, specificity and accuracy.
Methods: A sample of 67 high-risk individuals aged 35 years and above were selected. Their inclusion criteria were history of habits including smoking, alcohol consumption or betel quid chewing, with presence of primary squamous cell carcinomas (SCC), previously treated SCC or PMEL. The study was conducted in two phases. During the first phase of the study, Vizilite® was assessed on 40 subjects. In the second phase, Glowsticks and LED were assessed on 27 subjects. Biopsies were performed on identified lesions in 37 subjects. Another 14 subjects had no lesions. In the remaining 16 subjects, a biopsy was not performed due to subject's ill-health. The biopsy findings were correlated with the clinical observations.
Results: The sensitivity was 100% for all three diagnostic tools whereas the specificity was higher for Glowsticks and LED (90%) than for Vizilite® (85.7%). The accuracy was marginally higher for Vizilite® (96.8%) compared to the other two (95%).
Conclusions: Chemiluminescence and LED are effective in the early detection of oral cancer, dysplasia and PMEL. The LED may prove to be cheap, safe and non-invasive tool for screening high-risk individuals in clinics, health centres and remote areas devoid of modern healthcare facilities.

Schlagwörter: oral cancer, chemiluminescence, vizilite, glowsticks, LED

Poster Award: Merit Award

Konferenz/Veranstaltung:
07.08.2003 to 09.08.2003
Science and Technology Exposition 2003
Putra World Trade Centre, Kuala Lumpur, Malaysia

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 266,  Sprache: Deutsch
Die Fibrinmembran als Scaffold für ein rein autologes Bone Tissue Engineering
Nolting, Tim/Szuwart, Thomsas/Wiesmann, Hans-Peter/Joos, Ulrich/Kleinheinz, Johannes

Autologous bone tissue engineering is aimung at the extracorporal rebuilding of lost bone using exclusively cells and matrix from the receiver organism which were manufactured, cultivated and combined in vitro. The aim of this study was to establish a autologous carrier matrix for cells and proteines consisting of fibrin and to characterize the properties of this 100% autologous construction in vitro and in vivo.
Eight minipigs were used for manufacturing of the bone substitute using osteoblasts from the calvarian periosteum and endothelial cells from the jugular vein. Cells were cultivated until confluent stage and then seeded on a fibrin matrix based on autologous blood serum, combined with a autologous platelet-rich-plasma-concentrate and replantet in a critical size defect of the mandible. Specimens were taken at day 7 and 14 and analysed. Simultaneous attachment, proliferation, and differentiation of the cells on the carrier matrix was evaluated.
In vitro results demonstrated complete attachment of the cells on the matrix surface after 6 hours and distinctive proliferation of both cell types after 48 hours without any apoptotic signs. In 6 of the 8 animals histomorphometric analyses revealed an accelerated bone regeneration. Immunohistologic staining for endothelial cells showed an increased angiogenic front within the fibrin matrix, which was clearly in front of the osteogenic front. With the help of cell tracking technique it was possible to identify the transplanted cells over the whole period of investigation.
With this study we could demonstrate the possibility of creating a total autologous bone substitute. Based on vital transplanted cells and the nature of the matrix this construction is able to regenerate a bony defect in a fast and reliable manner.

Schlagwörter: Autologes Tissue Engineering, Fibrin, Endothelzellen, Osteoblasten, Autologous tissue engineering, fibrin, endothelial cells, osteoblasts

Poster Award: DGZMK/Dentsply/BZÄK Förderpreis

Konferenz/Veranstaltung:
30.09.2004 - 02.10.2004
128. Jahrestagung der Deutschen Gesellschaft für Zahn-, Mund- und Kieferheilkunde
Stuttgart, Deutschland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 244,  Sprache: Englisch
Facial Profile Support by Fixed or Removable Implant Superstructures
Neugebauer, Jörg/Meul, Britta/Kübler, Alexander C./Karapetian, Viktor Emil/Saffar, Mitra/Zöller, Joachim E.

Tooth loos and the resulting atrophy of the alveolar crest are causing loos of vertical height. A change in the profile with loos of the lip contour is recognized as sign for an old person.22 edentulous patients were analysed for the soft-tissue profile and phonation before and after implant prosthetic rehabilitation. 6 patients received a fixed reconstruction and 16 patients were treated with a removable bridge in the upper and lower jaw.The orthodontic profile analysis was used to determine the change of the position of the following points: Subnasale, Labrale superior, Labrale inferior, Stomium superior, Stomium inferius, Submentale. As reference points Glabella und Cervicale were used after the determination of the bite.After implant prosthetic rehabilitation in all cases the profile was developed ventral. The minimum and maximum values are shown together with mean value and median.
The incorporation of implant-borne superstructure leads to a support of the lip profile for all patients.The reconstruction with fixed superstructure showed a reduced increase of the profile in comparison to the removable bridges. An individual resin base could improve the vestibular contour.The phonation showed better results with the removable superstructures due to less necessary lab adaptations in comparison to the fixed bridges.

Schlagwörter: removable fixed implant restoration, profile support, vertical dimension, orthodontic profile analysis

Poster Award: Best Prosthetic Poster-Presentation

Konferenz/Veranstaltung:
April, 5-7th, 2003
International Congress on Reconstructive Preprosthetic Surgery Joint Meeting with California Association of Oral and Maxillofacial Surgeons
Palm Springs/California/USA

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 235,  Sprache: Englisch
Oily calcium hydroxyde suspension and alpha-TCP in treating intrabony defects
Stratul, Stefan-Ioan/Sculean, Anton

An oily Calcium Hydroxide suspension has been shown to enhance healing of various types of bone defects. The aim of this study was to evaluate de effect of a combination of an oily Calcium Hydroxide suspension (Osteoinductal®, Osteoinductal GmbH, Muenchen, Germany) with α-TCP (BioBase® α -pore, Biovision GmbH, Ilmenau, Germany) vs. α -TCP alone in the treatment of one- and two-wall intrabony pockets. 12 patients with moderate to severe chronic periodontitis and displaying a total of 26 intrabony defects were included in the study. The intrabony defects were randomly treated with either α-TCP alone or with the combination of α-TCP and Osteoinductal®. The following parameters were evaluated at baseline and six months after surgery: probing depth (PD), gingival recession (GR) and clinical attachment level (CAL). Post surgical care included administration of antibiotics (Amoxycillin) 3x500mg daily for one week and 0.2% chlorhexidine rinses twice daily for two weeks. At six months after surgery the results revealed in the combination group a mean CAL change from 8.07±1.44 mm to 4.21±1.81 mm (p

Schlagwörter: periodontal regeneration, oily calcium hydroxide suspension, alpha-TCP

Poster Award: DGP Travel Grant

Konferenz/Veranstaltung:
June, 19-21th, 2003
EUROPERIO 4
ICC Berlin/Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 238,  Sprache: Englisch
Failure mode of implant-abutment connections after horizontal cyclic loading
Zipprich, Holger/Weigl, Paul/Fischbach-Sedlatschek, Silke/Lauer, Hans-Christoph

Introduction and Objectives: Implant-abutment connections (IAV) show in vivo loosenings (L) and fractures (F) probably as a result of preceding micro movements (MM). The failure modes and their causes shall be evaluated. Material and method: 9 IAV types ∅ = (4-5 mm, n=8) were exposed to 106 cyclic loadings each, (100 N, 90° to the implant axis, at a distance of 8 mm from the IAV). In addition to this, the actual force on the IAV per cycle was measured. A computer-assisted sound analysis was used for the online detection of MM, L and F. For the analysis of L and F X-ray, REM and light microscopic photos were used. At the IAVs which remained intact, the was measured as well. (the moment of solve of the abutment was intended.) Results: Two IAV types didn't show any failure modes, but wear traces at the connection areas as can be proved. By one IAV type, a MM was detected preceding a L. Fractures at the connection screws and the abutments appeared at six IAV types. Only at one IAV type implant fractures occured. At none conical IAV types the failure frequency correlates with decreasing implant-diameter. However, at conical IAVs there is no correlation between failure frequency and implant-diameter. Summary: The occurrence of wear traces or failure modes (MM, L, F) shows, that all of the IAVs, with regard to horizontal encumbrances, feature constructions-conditioned weaknesses, which, in case of a long -term osseointegration of implants, could lead to a clinical component-failure (constructional element-failure), particularly in case of single tooth implant restorations placed in the lateral region.

Schlagwörter: implant, abutment, failure mode, screw, fracture, loosening, Implantat, Aufbau, Pfosten, Versagensmodi, Schraube, Fraktur, Lockerung

Poster Award: 3. Platz des 17. DGZMK / BZÄK / DENTSPLY Förderpreises

Konferenz/Veranstaltung:
October, 16-18th, 2003
DGZMK
Aachen/Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 163,  Sprache: Englisch
Evaluation of dental restorations with occlusal surfaces - A new approach -
Rudolph, Heike/Schöne, Christine/Weber, Anke/Benzinger, Silke/Quaas, Sebastian/Sporbeck, Henning/Luthardt, Ralph

Mainly, the occlusal fit of prosthodontic restorations is evaluated qualitatively by visual control of color-marked contact points. A large loss of data and information is immanent in conventional methods for the exploration of internal, marginal and occlusal fit of fixed restorations. Aim of this study was to develop a procedure for the three-dimensional analysis of internal and occlusal precision of fit.
A test model was developed by reverse engineering. Every single step in the manufacturing of fixed prosthodontic restorations concerning the influence on the achievable precision has to be evaluated. The test model is based on a real and an identical virtual model of upper and lower teeth in static occlusion. The interpenetration of upper and lower tooth surfaces may be evaluated qualitatively analogous to the analysis of occlusal contacts in conventional methods. On top of this, a quantitative evaluation of the size of the contacts is possible.
By multi-step optimization, manufacturing a real model in static occlusion, which is identical to a virtual model is considered to be possible within a processing error of

Schlagwörter: CAD/CAM, digitizing, restoration, occlusion, method

Poster Award: Tagungspreis für die beste Präsentation

Konferenz/Veranstaltung:
26.04.2002-27.04.2002
3. wissenschaftliche Tagung des Arbeitskreises für Angewandte Informatik in der Zahn-, Mund- und Kieferheilkunde
Münster

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 166,  Sprache: Deutsch
Klinische Untersuchung zur Wirksamkeit eines neuen Ulraschallgerätes bei der nicht-chirurgischen Parodontitis-Therapie
Horodko, Martin/Bürklin, Thomas/Raetzke, Peter/Ratka-Krüger, Petra

Mechanical debridement and biofilm removal from periodontally diseased root surfaces form an integral part of initial periodontal therapy. This is usually achieved with traditional hand instruments, sonic-, ultrasonic, or oscillating scalers. Aim of this study was the clinical investigation of a novel ultrasonic device (Vector, Duerr, Bietigheim, Germany) with a new approach of creating ultrasonic vibration, compared to scaling and root planing with hand instruments for non-surgical periodontal therapy. 14 patients were treated using either the Vector device or manual scaling and root planing in this controlled, prospective split-mouth study. 3 months after treatment probing depth and degree of inflammation were reduced in both groups, with relevant differences between the two groups. However, a significant gain of clinical attachment was found in the Vector-group.

Schlagwörter: chronische Parodontitis, Scaling und Wurzelglättung, Handinstrument, Vector-System

Poster Award: 3. Tagungsbestpreis

Konferenz/Veranstaltung:
12.09.-14.09.2002
Jahrestagung der Deutschen Gesellschaft für Parodontologie
Baden-Baden

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 168,  Sprache: Englisch
Immediate Bridge Restored Implants Under Functional Loading - A Study in Mini-Pigs -
Neugebauer, Jörg/Thams, Ulf/Roman, F. San/Steveling, Helmut G./Zöller, Joachim E.

Immediate loading of dental implants in the partially edentulous patient has not been investigated widely. Immediate loading requires immobilization of the implants by the superstructure (Ledermann, Brunski). An animal study was performed to evaluate the clinical success and the bone metabolism during the course of osseointegration on 12 implant borne bridges. Three month after tooth extraction implant insertion and prosthetic treatment was per-formed. 29 implants out of 62 had an insertion tor-que (IIT) above 35 Ncm. The average insertion tor-que of the implants per bridge (BIT) were determined. If the BIT was higher than 35 Ncm the bridges were successful after 3 month of loading. The histological findings of loaded and unloaded implants will be presented. The procedure with pre-fabricated auxiliary parts allows fabricating a bridge reconstruction during one appointment.

Schlagwörter: immediate loading, histological analysis, implant insertion torque, bridge

Poster Award: 1st Prize for Best Poster

Konferenz/Veranstaltung:
March 14-16, 2002
17th Annual Meeting Academy of Osseointegration
Dallas/Texas

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 131,  Sprache: Deutsch
Ohrgeräusche, kraniomandibuläre Dysfunktionen und deren Einfluss auf die Lebensqualität einer populationsbasierten Probandengruppe
Bernhardt, Olaf/Gesch, Dietmar/Mundt, Thorsten/Schwahn, Christian/Meyer, Georg/John, Ulrich

The aim of the present investigation was to evaluate several signs and symptoms of TMD as co- factors for tinnitus using data of 3124 subjects of the population based cross-sectional study 'Study of Health in Pomerania' (Ship). The screening was performed with the help of a multivariate logistic regression model which was adjusted for gender, age, and a variety of anamnestic and examined data. The target variable 'tinnitus' was formed from the combination of often- or constantly occurring tinnitus and examination by an ear-nose-throat specialist. As independent variables, the following variables were tested for significance in the logistic regression model: 1. Findings: gender, palpation pain in TMJ or masticatory muscles, pain upon maximal mandibular movement, deviations from straight mouth-opening of > 2 mm, facettes in dental hard tissue and restorations; 2. Anamnestic data: age, (categorized, adjusted according to the first age group), frequent headaches, frequent clenching of the teeth, frequent bruxism, physical complaints of unknown origin, anxiety attacks, worry, unfounded intense fears, agoraphobia, persistent sadness, persistent fatigue and listlessness, persistently overexcited and irritated, existential worry about occupation, high noise levels on the job. Furthermore the impact of signs and symptoms of TMD and tinnitus on the quality of life of this population-based sample was evaluated using the questionnaire SF-12 taken from Bullinger und Kirchberger.Increased Odds Ratios were found for palpation pain of the masticatory muscles (OR=2.3), teeth clenching (2.9), and listlessness (3.1) in females and for frequent headache (6.2) and listlessness (2.1) in males. A relationship between tinnitus and TMD was established only for males. Both disorders may be stress-induced.

Schlagwörter: tinnitus, TMD, epidemiology, quality of life

Poster Award: Tagungsbestpreis, Preis für das beste Poster

Konferenz/Veranstaltung:
1.12.01
34. Jahrestagung der Arbeitsgemeinschaft für Funktionslehre
Bad Homburg

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 132,  Sprache: Deutsch
Untersuchungen zu Effekten des Vector-Systems
Hartschen, Vera Juliane/Frentzen, Matthias

Recently a new ultrasonic system was introduced using a different type of energy transmission in order to offer a less abrasive and less painful therapy. The aim of the present study was to investigate the effects of this system in combination with the straight metal probe compared to conventional ultrasonic and hand instrumentation.
50 extracted decapitated teeth were randomly assigned to 5 groups (n=10). Group 1 was treated with a Gracey curette No. 5 for 3 minutes, group 2 and 3 with the Siroson® S ultrasonic tip for 3 minutes/6 minutes, group 4 and 5 with the Vector®-system for 3 minutes/6 minutes. The Vector®-system was used in accordance with the manufacturer's manual. The samples were fixed in an artificial periodontal socket to simulate a periodontal lesion. Before and after treatment the root surfaces were documented by micrographs. For histological examination the undecalcified samples were cut lengthwise into sections of 20-30 µm thickness. In addition, the treated surface was investigated with SEM using a replica technique. The effects on the root surface were documented by scoring the presence of debris. Descriptive analysis was proved by the Kruskal-Wallis test and Wilcoxon signed rank test.
Micrographic analysis showed a most complete calculus removal after hand instrumentation. The conventional ultrasonic system was more effective than the Vector® treatment. SEM evaluation of the hand instrumentation presented a characteristic surface. The conventional ultrasonic system left an irregular surface with smooth areas as well as small defects. The Vector®-system revealed a similar texture as the conventional system. The results were supported by the histological examination.
In conclusion the treatment of the root surface with the new ultrasonic device in combination with the straight metal probe resulted in a less effective removal of calculus and more tooth substance preserving procedure.

Schlagwörter: ultrasonic instruments, curettes, debridement, root planing, SEM

Poster Award: 3. Preis (Tagungspreis)

Konferenz/Veranstaltung:
13.-15.September 2001
Jahrestagung der Deutschen Gesellschaft fuer Parodontologie
Luebeck, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 133,  Sprache: Englisch
Determining the Wear Resistance of Occlusal Splints in a Prospective Clinical Study
Ottl, Peter/Schmelz, Petra/Piwowarczyk, Andree/Lauer, Hans-Christoph

Objective: The objective of this study was to determine quantitatively the wear resistance of a newly developed light-curing resin for two different types of occlusal splints over a period in situ of six months.
Materials and Methods: The study included two samples of ten patients each that had been provided with either stabilization or distraction splints. These occlusal splints were repositioned on remount casts and the occlusal aspect was surveyed prior to insertion and at the four-week, three-month, and six-month recalls. The test setup consisted of an anti-vibration table framework, three translation stages, an inductive displacement transducer, a stereomicroscope, and a digital measurement unit for data acquisition and analysis. The coordinates for the occlusal contacts were stored at the baseline examinations and reproducibly sought out during the recall examinations. Each examination included ten repeat measurements each in the regions of teeth 13, 23, 16, and 26.
Results: After six months, the stabilization splints showed a median vertical gain of 1 µm in the region of tooth 13 and a median vertical loss of 24 µm in the region of tooth 23. Regions 16 and 26 exhibited median vertical losses of 37 µm and 33 µm, respectively. In the second sample (distraction splint), the corresponding vertical loss values were 1 µm (tooth 13), 23 µm (tooth 23), 33 µm (tooth 16), and 64 µm (tooth 26). Statistical analysis (Mann-Whitney U-test, p Conclusions: The present study clinically confirms the good wear resistance results of the new resin splint material obtained in a previous in-vitro study [Ottl et al., Dtsch Zahnärztl Z 52, 342 (1997)]. This parameter is of great importance for maintaining the therapeutic mandibular position during the treatment period.

Schlagwörter: craniomandibular disorders, temporomandibular joint, clinical follow-up study, occlusal splint therapy, resin, wear resistance

Poster Award: Best Poster of Conference

Konferenz/Veranstaltung:
May 17-19, 2001
50th Annual Meeting of the "Deutsche Gesellschaft für Zahnärztliche Prothetik und Werkstoffkunde"
Bad Homburg, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 127,  Sprache: Deutsch
Einfluß einer Taschenirrigation auf die elastolytische Aktivität in der Sulkusflüssigkeit
Herrmann, Jens Martin/Gonzáles, José Roberto/Meyle, Joerg

Organic oils, like those used in mouthrinses can, due to their hydrophobe behavior, contribute to the dilution or eluation of substances from periodontal pockets, if they are used for subgingival irrigation.Neutrophil elastase is a proteolytic enzyme known for its destructive potential also of periodontal tissues. Its activity in gingival crevicular fluid (GCF) is a suitable marker to monitor periodontal and gingival inflammation.
The aim of the present study was to determine the effect of two different solutions for pocket irrigations on the elastolytic activity (EA) in GCF.
In a prospective, randomized double-blind study 20 patients with severe chronic periodontitis were included based on radiographic and clinical parameters. They had at least 3 teeth in the upper jaw with one site probing pocket depth (PD more than 5 mm).
After a period of initial plaque control (14 days) an examination phase of 90 days followed.
The clinical parameters assessed were a modified plaque index (PLI), 4 sites/tooth, as well as probing pocket depth, bleeding on probing (BOP) and attachment level at 6 sites/tooth. On the days -14, 0, 15, 28, and 90 the patients underwent a complete clinical examination. All clinical measurements performed were using a Florida Probe® and reference acrylic stents.
During the experimental phase, prior to clinical examination two samples of GCF were taken at 3 test teeth using Periopaper® on the days 0, 1, 3, 15, 28, and 90. After sample collection and clinical probings all sites PD more than 5 mm were rinsed. The liquids used were 1 ml of oil in the test group respectively 0,9% NaCl in the control group.
The sample volumes were analyzed with Periotron 8000® and the elastolytic activity was measured with the Fluostar®. In the test group a decline of the median - EA from 2839 µU/µl (day 0) to 1892 (day 1) and 1137 µU/µl (day 3) could be observed. At the end of the study the median -EA had reached its initial level again. The control group did not show any comparable findings.The results show that a subgingival irrigation with soy bean oil in this frequency decreases EA of inflamed periodontal pockets considerably.

Schlagwörter: soy bean oil, pocket irrigation, elastolytic activity, gingival crevicular fluid, periodontal therapy, Florida Probe, Periotron 8000, Periopaper, Fluostar

Poster Award: 3. Bestpreis (Kategorie Poster)

Konferenz/Veranstaltung:
13. - 15.09.2001
Wissenschaftliche Jahrestagung der DGP 2001
Musik- und Kongresshalle Lübeck

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 107,  Sprache: Deutsch
Die Langerhanszell-Histiozytose mit multiplen eosiniphilen Granulomen im Ober- und Unterkiefer
Kleier, Christian/Kleinheinz, Johannes/Joos, Ulrich

The diagnosis Langerhans' cell histiocytosis subsumes different granulomatous lesions of unknown origin. Regarding the literature there are controversies about the disease being a reactive process, a neoplasm or a malignancy. The chronic generalised form compasses the trias exophthalmus, insipid diabetes which is due to a compression of the pituitary stalk, and multiple osteolytic defects of the skull. The latter is accepted to be an obligate sign. The case of a 30 year old male is presented in which histological and immunohistological evidence was made of multiple eosinophilic granulomas of the upper and lower jaw. At the time of making the diagnosis there was an insipid diabetes. The treatment was planned according to suggestions of an interdisciplinary conference and consisted of two six weeks cycles of chemotherapy with vinblastin and prednisone. The aim was to preserve teeth and alveolar process. After the chemotherapy biopsies were taken from the former affected regions which were negative. Despite the chemotherapy an apposition of bone was determined in the molar region of the lower jaw that a prosthetic rehabilitation was initiated. In comparison to similar cases the course of the disease is different and not predictable. It's control has to be implemented by regular radiographic examination and possible biopsies because of the lack of specific tracers.

Schlagwörter: Langerhans' cell histiocytosis, eosinophilic granuloma of the jaws, immunohistology, chemotherapy, prognosis, Langerhanszell-Histiozytose, eosinophiles Granulom der Kiefer, Immunohistologie, Chemotherapie, Prognose

Poster Award: Poster-Preis der Tagung

Konferenz/Veranstaltung:
1.-3. Juni 2000
51. Jahrestagung der Arbeitsgemeinschaft für Kieferchirurgie innerhalb der Deutschen Gesellschaft für Zahn-, Mund- und Kieferheilkunde
Bad Homburg

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 103,  Sprache: Deutsch
Mikrotest zur Bestimmung der Elastaseaktivität bei marginaler Parodontitis
Herrmann, Jens Martin/Kleinsteuber, Andreas/Gonzáles, José Roberto/Vonholdt, Julia/Panagiotou, Ekaterini/Roessler, Ralf/Meyle, Joerg

Proteolytic enzymes from neutrophils play a decisive role in tissue destruction. They release from the granulocyte during the phagocytosis or by lysis. In addition to cathepsin D, cathepsin G and collagenase, elastase is a principal component in collagenfibers destruction. Not only elastin is affected by lysis produced from elastase, but also proteoglycanes, hemoglobin, fibrinogen and collagen. In 1975 Ohlsson and Delshammer investigated in gingival biopsies the connection between elastase concentration and the granulcytes contents. In diseased tissues the mean concentration of elastase was 0,1 µg/mm3. That concentration means a proportional content of 25.000 granulocytes. Kowashi and Cimasoni (1980) reported a connection between periodontal destruction and proteolytical activity in the gingival crevicular fluid flow. Important for tissue disintegration and destructive processes is not only the enzymatical concentration, but also the activity. Kenneth et al. (1995) reported about a periodontal disease progression with an amount of over an elastolytical activity from 300 µU/µl. Elastase can appeare as a complex with the alpha-1-proteinase-inhibitor or alpha-2-macroglobulin respectively.

Schlagwörter: Elastaseaktivität, Diagnostik, Mikrotest, Parodontitis

Poster Award: Posterbestpreis

Konferenz/Veranstaltung:
Wissenschaftliche Jahrestagung der DGP
27.09.97
Leipzig

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 87,  Sprache: Englisch
Einfluß verschiedener Mundspüllösungen auf in vivo gewachsene Plaque
Hombach, Andreas/Beetke, Eckhard/Jentsch, Holger

A lot of publications are about the chemical influence of mouthrinses on dental plaque. Most of this investigations are in vitro methods of testing. Ultrastructure analysis of dental plaque are seldom published and mostly done with a scanning electron microscope. The aim of this study is a quantitative comparison between effects of different antimicrobial mouthrinses on dental plaque in vivo. This quantitative investigation was realized with the method of transmission electron microscopy (TEM).
21 adults aged 18 to 62 years participated randomized in a three days study. The subjects wore plastic splints with three pieces of bovine enamel in the molar area of the lower jaw. An amine fluoride / stannous fluoride mouthrinse (ASF) in group 1, 0.12 % chlorhexidine digluconate mouthrinse (CHX) in group 2 and 0.7 % sodium chloride mouthrinse (SCL) in group 3 have been used for rinsing. The rinsing procedure was executed with 10 ml mouthrinse for 30 seconds twice a day. 24 (a), 48 (b) and 72 (c) hours after baseline each a piece of enamel with the plaque layer was removed and prepared for TEM. Ultrathin slices were inspected relating to plaque thickness (PT in µm), quantity of cocci (QC per 10 µm2) and quantity of rods (QR per 10 µm2). Friedman-/Wilcoxon-Test was used for statistical analysis.
The results for group 1 are: PT/a 8.42±3.66, PT/b 11.65±5.27 (p=0.018), PT/c 14.02±6.37 (p=0.018); QC/a 15.68±6.16, QC/b 18.08±9.50 (n.s.), QC/c 12.04±5.37 (p=0.018); QR/a 0.23±0.19, QR/b 0.81±1.23, QR/c 0.52±0.44 (n.s.). The results for group 2 are: PT/a 6.91±5.97, PT/b 9.98±6.27 (p=0.018), PT/c 11.91±7.00 (p=0.018); QC/a7.02±4.01, QC/b 7.52±5.27 (n.s.), QC/c 4.29±3.76 (p=0.018); QR/a 0.21±0.47, QR/b 0.25±0.22, QR/c 0.08±0.13 (n.s.). The results for group 3 are: PT/a 4.69±1.88, PT/b 10.60±5.31 (p=0.018), PT/c 19.24±5.70 (p=0.018); QC/a 14.25±3.78, QC/b 16.98±2.82 (p=0.018), QC/c 18.18±2.60 (p=0.018); QR/a 0.52±0.18, QR/b 0.88±0.19 (p=0.018) QR/c 1.29±0.37 (p=0.018). All groups showed significant changes at PT and QC, group 3 showed additionally a significant increase of QR.
The results permit the conclusion that the effects of ASF and CHX relating to plaque thickness and quantity of cocci as wel as start of efficacy are very similar.

Schlagwörter: mouthrinses, dental plaque, transmission, electron microscopy

Poster Award: Dentsply - Förderpreis

Konferenz/Veranstaltung:
16. bis 18.11.2001
BZÄK- DGZMK- Tagung
Frankfurt/Main, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 70,  Sprache: Deutsch
Funktionsstörungen des Kauorgans und allgemeinmedizinische Erkrankungen: Risikofaktoren und Marker für Kopfschmerzen
Bernhardt, Olaf/Gesch, Dietmar/Mundt, Thorsten/Mack, Florian/Schwahn, Christian/Meyer, Georg/Hensel, Elke/John, Ulrich

Temporomandibular disorders (TMD) are supposed to be also possible risk factors or co- factors for general medical diseases. Correlation to specific headache symptoms, tinnitus and spinal pain disorders are established. The aim of the present investigation was to evaluate several signs and symptoms of TMD as a co- factor for frequent headache using a population based sample of the ongoing cross-sectional epidemiological study 'Study of Health in Pomerania' (Ship).
Medical, dental and sociodemographic parameters of 3146 representatively and according to age distribution selected subjects (age distribution 20-80 years) were checked for correlations with frequent headache symptoms using a multivariate logistic regression model. Frequent headache was defined asking the question: Do you suffer from following diseases: - headache, if yeas 1.
sometimes 2. often.3. always. Only the appearance of sometimes or often headache were used defining the variable. The model was adjusted for age, sex, level of education, income, TMD- symptoms and 32 chronic diseases. Significant values for the calculated odds ratios (OR) for the whole sample were found for pain on palpation of the masticatory muscles: 1-3 muscles painful: OR= 2.6, = muscles painful: OR= 4, tinnitus: OR = 2.8, sleeping disorders: OR= 1.9 and education level: OR= 2.0. The palpation pain of the muscles showed a dose dependence. As not significant turned out, to be smoking, alcohol abuse, and income, questions for pain in the TMJ- area, TMJ clicking, positive questions for several chronic diseases and education level. Gender separated regression models confirmed in general the results.
In this study we found, using an adjusted multivariate logistic regression model a significant and dose depended association between frequent headache and masticatory muscle pain.

Schlagwörter: Kopfschmerzen, Funktionsstörungen, orofaziales System

Poster Award: Tagungsbestpreis 2000 der Arbeitsgemeinschaft für Funktionslehre

Konferenz/Veranstaltung:
24.11.2000-25.11.2000
Jahrestagung der Arbeitsgemeinschaft für Funktionslehre in der DGZMK
Bad Homburg

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 71,  Sprache: Deutsch
Vergleichende Prüfung verschiedener Methoden der Kariesrisiko-Diagnostik
Kühnisch, Jan/Heinrich-Weltzien, Roswitha/Stößer, Lutz/Senkel, Helga

The aim of this study was to assess the caries risk in 450 8-year-old Westphalian children by the clinical methods of the 'DAJ-criteria', the 'Schieber zur Kariesrisiko-Bestimmung' and the 'Dentoprog-method'. Caries was recorded using WHO diagnosing criteria. The caries risk was assessed for each child with all methods.
79.1% of the children had caries free permanent teeth. The mean caries experience was 7.6 dfs and 0.7 DMFS. Using the 'DAJ-criteria' (dft/DMFT > 5/7 or DT > 0/2) 19.8% of the 8-year-olds were identified at risk. By the 'Schieber zur Kariesrisiko-Bestimmung' a high caries risk was predicted for 47.8% of the children. Both methods agreed in 71% of low and high caries risk assessment. Comparing the agreement of the 'Schieber zur Kariesrisiko-Bestimmung' and the "Dentoprog-method" in caries risk assessment the same categorization was found for 94% of the children. The positive correlations (Spearman) of the risk predictors used by the 'Schieber zur Kariesrisiko-Bestimmung' and the "Dentoprog-method" compared to the caries prevalence as well as to the low number of caries free mixed dentitions (32%) indicated a correctly classified caries risk group with the 'Schieber zur Kariesrisiko-Bestimmung'.
This study suggests that the 'Schieber zur Kariesrisiko-Bestimmung' should be recommended as preventive orientated method for identification of caries risk patients in the annual dental examination by the dentists of the public health care system.

Schlagwörter: Kariesprävalenz, Kariesrisiko-Einschätzung, DAJ-Kriterien, Dentoprog-Methode, Schieber zur Kariesrisiko-Bestimmung

Poster Award: Preis 1998 der Gesellschaft für Kinderzahnheilkunde und Primärprophylaxe in der DGZMK

Konferenz/Veranstaltung:
25.-26.09.1998
5. Jahrestagung d. Ges. Kinderzahnheilkunde und Primärprophylaxe in d. DGZMK
Dresden

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 67,  Sprache: Englisch
Interleukin - 10 Polymorphisms in Patients with Early Onset- and Adult Periodontitis
Herrmann, Jens Martin/Gonzáles, José Roberto/Michel, Jörg/Diete, A./Wunderlich, D./Vonholdt, Julia/Meyle, Joerg

Different cytokine genotypes have been described in periodontal disease. The aim of the present study was to investigate the genetic association of interleukin-10 (IL-10) polymorphisms in patients with early onset- (EOP) and adult periodontitis (AP) and to investigate possible associations with clinical manifestations. Based on clinical parameters and radiographs, 23 patients with AP and 18 patients with EOP were included in the study. Additionally, 21 healthy subjects, who were age-matched, were included as a control group. Genomic DNA was isolated from whole blood samples and the IL-10 promoter positions -597 and -824 were amplified by polymerase chain reaction (PCR). Polymorphisms were detected by restriction-enzyme cleavage. No statistical significance in the allele frequencies between patients and controls could be demonstrated. The *A and *C alleles at the -597 position were associated with the *T and *C alleles at the -824 position, respectively. We conclude that the investigated polymorphisms are not associated with periodontal disease.

Schlagwörter: Interleukin - 10, Polymorphisms, Early Onset Periodontitis, Adult Periodontitis

Poster Award: Swiss Society of Periodontology Award

Konferenz/Veranstaltung:
08.06.2000-10.06.2000
Europerio III
Geneva, Switzerland

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 68,  Sprache: Deutsch
Defektweite zur Prognose und Beschreibung parodontaler Heilung in Knochentaschen
Klein, Filip/Kim, Ti-Sun/Haßfeld, Stefan/Staehle, Hans Jörg/Eickholz, Peter

Methods: In 24 patients with advanced periodontitis 39 intrabony defects were treated by the guided tissue regeneration technique using expanded polytetrafluoroethylene (n = 6) or bioabsorbable barriers (n = 32). Clinical parameters were assessed and 39 triplets of standardized radiographs were taken before, 6, and 24 months after surgery. Using a computer-assisted analysis the depth, width, and angle of the bony defects were measured.Results: Statisti-cally significant vertical attachment gains (CAL-V: 3.16 ± 1.63 mm / 3.29 ± 1.64 mm; P = 3 mm) intrabony defects bony fill was more pronounced than in wide and shallow defects (P

Schlagwörter: Knochentaschen, GTR, Defektwinkel, Defektweite

Poster Award: Tagesbestpreis der Gemeinschaftstagung der DGZMK, LZK Hessen und DGP

Konferenz/Veranstaltung:
16.11.2000-18.11.2000
Gemeinschaftstagung der DGZMK, LZK Hessen und DGP
Frankfurt a. M., Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 69,  Sprache: Deutsch
Quantitative REM-Untersuchung zur Biofilmbildung auf Titanoberflächen
Braasch, Volker/Schmitz, Inge/Müller, Klaus-Michael/Grimm, Wolf-Dieter

The purpose of this study was to characterize different Ti-surfaces using REM and spectroscopy (AES and EDX) and to compare the quantity of bacterial compositions on different titanium surfaces using quantitative SEM- in vivo studies for assessing the effects of material selection on bacterial cell responses. The cp titanium units were obtained from titanium grade 1 and 2 with smooth like transmucosal implant collar-surface topographies by using the Dentaurum -casting technique and the Procera -milling technique. Titanium specimens were positioned on to the teeth for monitoring the subgingival early bacterial adhesion at 6, 12 and 24 hours. The quantitativ assesment of diameters of bacterial layers was recorded by using the software system PC Images for Windows. Early bacterial adhesion on the intrasulcular Ti-surfaces showed a difference between the two Ti-samples (cp Ti grade 1 and 2). The count of particles and their diameters after all times of intraoral exposition measured were greater in the Cp-group than in the Re-group of specimens. The differences were statistically significant (Mann-Whitney-U-Test, p= 0,05).All titanium specimens showed either a continuous or a fragmented coating by colonizing bacteria. Surface analysis using Auger Electron Spectroscopy (AES) indicated that the oxide thickness and the subsurface composition of titanium influence subgingival early bacterial adhesion. The inhibitory CH2-groups covered the outer TiOx - layer and could not be identified on casted titanium surfaces.

Schlagwörter: Quantitative, REM-Untersuchung, Biofilmbildung, Titanoberflächen

Poster Award: Colgate Forschungspreis 2000

Konferenz/Veranstaltung:
16.11.2000-18.11.2000
124. Jahrestagung der Deutschen Gesellschaft für Zahn-, Mund- und Kieferheilkunde (DGZMK) gemeinsam mit der Deutschen Gesellschaft für Parodontologie und der Landeszahnärztekammer Hessen, Colgate-Forschungspreis 2000 der DGZMK
Frankfurt am Main, Germany

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 55,  Sprache: Englisch
New Aspects concerning X-ray Protection - Dose Reduction versus Diagnostic Information?
Segerath, Catrin/Stamm, Thomas/Renger, Bernhard/Ehmer, Ulrike/Heindel, Walter L.

In comparison to conventional screen-film combinations Digital Radiography (DR) offers several advantages, i.e. reduction of the x-ray exposure and the further option of image processing. It is an obvious controversy that collimated film areas provide information for cephalometric analyses. One of the most interesting side effects of DR is the possibility to perform a complete analysis of the entire scull in typically collimated lateral cephalograms.The aim of this prospective study was to determine the validity of this special image processing method developed by the Department of Orthodontics, University of Muenster.Out of 400 digital radiographs taken for orthodontic diagnosis, 100 lateral head films were randomly selected. The routine radiographs were taken from the Department of Radiology, University of Muenster. For each patient the facial cranium exclusively was faded in and exposed at 77kV/12 mAs with an anode to film distance of 350 cm.The digital image acquisition included laser-scanning (pre-read) of the storage phosphor plates, individual processing of every image (Pattern Recognition for Iris of Exposure Field - algorithm) and storing of the original and processed images using the DICOM - format.The intra-individual reproducibility of the landmarks defined by DELAIRE who proposed a cranial and craniofacial analysis was examined using the NIH-Image 1.62 analysis program.The results show that it is possible to attain information from collimated areas (cranial vault, cervical vertebra) using DR combined with special image processing methods. This is due to the x-ray scatter and the various contrast enhancements possible in different film areas of the same image.The information attained from these areas with very low x-ray load is sufficient for a complete cranial analysis proposed by DELAIRE, so that an increase of field size can be avoided in many clinical cases.For the first time since 1987 the gold standard of head film acquisition for the DELAIRE-Analysis proposed by PRECIOUS and MILES has been redefined.

Schlagwörter: Digitale Fernröntgenseitenbilder, digitale Lumineszenzradiographie,Strahlenreduktion, Delaire-Analyse

Poster Award: Posterpreis

Konferenz/Veranstaltung:
30.09.99-02.10.99
123. Jahrestagung der DGZMK und Ihrer Akademie Praxis und Wissenschaft,
50. Jahrestagung der Arbeitsgemeinschaft Kieferchirurgie,
21. Jahrestagung des Arbeitskreises Oralpathologie und Oralmedizin,
Maritim Congress Centrum Bonn

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 48,  Sprache: Englisch
Anaerobic microflora under class I and class II composite and amalgam fillings
Heinrich, Annegret/Bernhardt, Olaf/Splieth, Christian/Meyer, Georg

An assessment of microflora beneath restorations indicates how the antimicrobial activity of filling materials on residual microorganisms and whether the material prevents a penetration of microorganisms after its application. The aim of the present study was to determine a microbial spectrum under composite fillings compared to that under amalgam fillings. Ten composite and 5 amalgam fillings were evaluated for occlusal loss of material, marginal gaps, and secondary caries. After the removal of the fillings, a sample of carious dentine just below the filling was taken under sterile conditions and stored in a prereduced transport medium for anaerobs and immediately transfered to a laboratory for microbial diagnosis. Clinical examination showed in 50% of all restorations occlusal loss of material and marginal gaps. In 9 out of 10 composite fillings and 2 out of 5 amalgam fillings secondary caries was diagnosed. The ratios of aerobic to anaerobic flora were comparable. (under composite 11.4% : 88.6%) and amalgam 15.4% : 84.5%). The microbial variety under composite fillings was much greater compared to amalgam and it was similar to infected root canals (strict anaerobic gram-negative rods as Fusobacterum spp. Porphyromonas spp.). Quantitatively, there were up to 8 times more microorganisms under composite fillings. Beneath amalgam we found microbes similar to the flora of carious dentine and carious plaque, with anaerobe and facultative anaerobic gram-positive rods dominating. The kind of filling material may have an important influence on quantity and quality of the microbial spectrum in dental cavities. Associations between anaerobic gramnegative flora under composites and infected root canals need further investigations.

Schlagwörter: dental materials, microbiology, composite, amalgam

Poster Award: Best poster

Konferenz/Veranstaltung:
11.05.2000-13.05.2000
CONSEURO 2000
Bologna

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 37,  Sprache: Englisch
Evaluation of the temporomandibular joint by magnetic resonance imaging using a standardized evaluation form
Ottl, Peter/Hohmann, Andreas/Lauer, Hans-Christoph/Zanella, Friedhelm/Hardenacke, Frank

For the past 15 years magnetic resonance imaging (MRI) has increasingly been used in the diagnosis of craniomandibular disorders. The present standardized evaluation form was created to establish a more systematic approach to the evaluation of MRI images of the temporomandibular joint. The initial parameters to be evaluated are condylar morphology (compacta and spongiosa), fossa and tubercular morphology, and disk morphology. Next, the condyle/fossa relationship with the mouth open and closed, the disk position in two planes (coronal, vertical to the long axis of the condyle) with the mouth open and closed, and the bilaminar zone are examined. Finally, the T2-weighted signals in the condylar region, in the joint space, and in the bilaminar zone are evaluated. The MRI images presented originate from a retrospective study of 77 patients in whom an arthropathy of the temporomandibular joint was clinically suspected. The images were taken using bilateral temporomandibular surface coils and FLASH or SE sequences (T1 and T2 weighting) in two planes without using a contrast medium. The standardized evaluation form streamlines MRI diagnosis. Moreover, the risk that subsidiary findings might be missed is minimized.

Schlagwörter: craniomandibular disorders, CMD, temporomandibular joint, diagnosis, magnetic resonance imaging, evaluation form

Poster Award: Posterpreis der Tagung

Konferenz/Veranstaltung:
26.11.99-27.11.99
32. Jahrestagung der Arbeitsgemeinschaft für Funktionslehre in der Deutschen Gesellschaft für Zahn-, Mund- und Kieferheilkunde
Bad Homburg

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 33,  Sprache: Englisch
Experimental studies on surface treatment of Titanium by new blasting techniques
Lenz, Ulrike/Lenz, Edwin/Raser, Gerhard

In industrial technology surface treatment by micro-blasting and micro-peening are increasingly used as they reach a high degree of surface refinement and strengthening. These methods are of interest in dental technology, especially for the treatment of Titanium castings. The aim of the present investigation is the experimental evaluation of a micro-dry-blasting-method (Gruber and Stübinger, Linz/Austria), using an abrasive and a spherical blasting medium, separate and in combination. Cast samples (20x10x2 mm) of Titanium (grade 1) were used for the experiments. Their initial surface conditions were
- casted and cleaned in an ultrasonic bath
- wett grinded on SiC-paper, grit size 220, 600, 1200.
The finished surfaces were characterised by light- and scanning electron microscopy (SEM) and analysed profile-graphically (RZD, Sm). Surface near parts of the finished samples were light microscopically investigated on metallographic transverse sections. From the results the following conclusions can be drawn:
1. The abrasive micro-blasting of Titanium castings removes surface near layers and shows an levelling effect. Microstructural defects are extensively diminished.
2. Abrasive micro-blasting of surface ground before (SiC220) shows the same result, but in lower degree. Abrasive micro-blasting of fine-ground samples is of no use.
3. The micro-peening technique in combination with the foregoing abrasive microblasting or grinding effects a further levelling and compaction of the surface. The average distances of the peaks are increased.
The investigated methods enable a rationalisation of surface finishing and an improvement of surface quality of Titanium castings. Their combination with usual milling and polishing methods of dental laboratories was tested and can be recommended.

Schlagwörter: finishing of Titanium, shoot peening, abrasive micro-blasting, surface levelling and compaction, metallographic structure, roughness

Poster Award: Quintessenz Poster Prize 1999

Konferenz/Veranstaltung:
09.10.99-11.10.99
23rd Annual Conference of the Prosthodontic Association (EPA)
Sevilla/Spanien

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 26,  Sprache: Deutsch
Infektionen im Mund-, Kiefer- und Gesichtsbereich: Was hat sich in den letzten 25 Jahren geändert?
Al-Nawas, Bilal/Grötz, Knut A./Mäurer, Markus/Wagner, Wilfried

In a prospective randomised study in hospitalised patients in the year 1973 and 1998 microbial findings in odontogenic abscesses and wound infections were recorded. In severe odontogenic abscesses the profile of bacteria changed: the "typical" Gram positive pathogens, which predominantly identified in 1973 were less frequently observed in the recent study episode. In contrast, the number of Gram negative bacteria appears to be increased in 1998. Additionally, the number of culture negative episodes in severe odontogenic abscesses seems to be increased. In the group of patients with post operative wound infections the number of Gram negative bacteria remains unchanged, accounting for >50% of the culture positive episodes. In the data from 1998, a high incidence of anaerobes is found in both groups of patients, emphasising the need for routine testing of these pathogens. Yeasts identified in both patient groups seem to have increased but their pathogenic role has to be further elucidated.

Schlagwörter: Rahmenlose Stereotaxie, computergestützte Chirurgie, Zygomaticus Fixture, Tumorchirurgie

Poster Award: Posterpreis der Tagung

Konferenz/Veranstaltung:
30.09.99-02.10.99
123. Jahrestagung der DGZMK gemeinsam mit der Arbeitsgemeinschaft für Kieferchirurgie, Bonn

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)

Poster 22,  Sprache: Deutsch
Permeationsverhalten verschiedener Handschuhe bei Einwirkung eines alkoholischen Händedesinfizienz
Rath, Birgit/Baumann, Michael A.

The usage of gloves in dentistry has increased greatly over the last ten years and this highlighted certain problems when they have been worn extensively. While skin irritations and allergies caused by latex proteins and accelerators have been the main focus of attention, dental materials such as disinfectants have also become known as a source of skin reactions. This study was performed to evaluate the permeability of various gloves by ethanol. The tip of the middle finger of ten glove brands (natural latex gloves (NLG) powdered or unpowdered, powdered vinyl and synthetic elastomer) was exposed to 5 ml of a hand disinfectant (Desderman TM). After a penetration time ranging from 2 minutes to 8 hours the permeation of Desderman was detected with a gas chromatograph (F45, Perkin-Elmer). Only one component of the disinfectant (ethanol) could be detected to have gone through the gloves. After only 2 minutes the vinyl glove and after 10 minutes all glove types were permeated. Natural latex gloves of a higher price showed a tendency to a lower rate of leakage and the synthetic elastomer (Biogel Neotech TM) was the only one with a significantly lower penetration after even 2-8 hours.

Schlagwörter: digital dental radiography, CCD sensor, storage phosphor, dose reduction

Poster Award: DGZMK/Regent-Förderpreis 1998

Konferenz/Veranstaltung:
21.05.98
49. Jahrestagung der Arbeitsgemeinschaft für Kieferchirurgie
Bad Homburg

 Abstract ein-/ausblenden      Volltext (html)    

Poster 10,  Sprache: Deutsch
Bestimmung der Zahnangulation im Dental-CT bei nicht konstanten Untersuchungsparametern
Sellerer, Steffen/Hirschfelder, Ursula

Aim: In order to achieve anatomically correct measurements of the tooth axes in Dental CT, a standard evaluation framework is necessary because there is no possibility to fix the patient's head in CT.
Material: A macerated skull and 23 patients with full dentitions.
Methods: A macerated skull with a titan plate in the occlusal plane was scanned in four different positions. In this presentation an example is given by the images of the skull tilt 7° to the left. In the first step the angulations of the teeth were measured to the horizontal edge of the panoramic and paraxial CT reformations (original measurements). These values were entered into a self developed angulation correction program based on a defined reference compared with the original measurements and with the values which were obtained by plane (occlusal plane). The corrected values were then measuring the angle between the tooth axes and the titan plate (control measurements). The results were analysed statistically. In addition, the Dental CT images of 23 patients partly with misplaced teeth were analysed analogously.
Results: For the macerated skull the difference between the corrected values and the control measurements was up to 1°. However the difference between the original measurements and the corrected values was up to 7°. In the panoramic images the greatest deviation could be seen in the anterior area and in the paraxial images in the posterior area of the dental arch. For the patients about 67% of the tooth axes could be measured easily whereas the determination of the tooth axes was insufficient in 33% of the measured teeth.
Conclusion: Overall, the Dental CT is most suitable to find the topographical location of misplaced and impacted teeth. The angulation correction program, especially developed for this application, guarantees an exact metric analysis of tooth angulation independent of the patient's position in the CT. Dental CT and the angulation correction program form an optimal diagnostic instrument for presurgical planning and for orthodontic procedures, especially in cases having misplaced teeth.

Schlagwörter: dental, CT, tooth angulation, dental-CT, computer correction program

Poster Award: BZÄK/DGZMK/Dentsply-Förderpreis 1998

Konferenz/Veranstaltung:
15.10.98-17.10.98
122. Jahrestagung der Deutschen Gesellschaft für Zahn-, Mund- und Kieferheilkunde
Bremen

 Abstract ein-/ausblenden      Volltext (html)      Poster Image (jpg)